Evidence map›Paper›PMID 34298946›Full record

ArticleInternational journal of molecular sciences2021

Tumor Cell-Specific 2'-Fluoro RNA Aptamer Conjugated with

Mariya A Vorobyeva, Maya A Dymova, Darya S Novopashina, Elena V Kuligina, Valentina V Timoshenko, Iaroslav A Kolesnikov, Sergey Yu Taskaev, Vladimir A Richter, Alya G Venyaminova

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 31 citations in OpenAlex.

  1. Advances in Aptamer Drug Delivery Systems for Treatment of Glioblastoma.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  2. Article
  3. Review
  4. Chemotherapy sensitivity of primary glioblastoma cells and immunohistochemical markers to predict of survival of patients with of glioblastoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  5. Article
  6. Review
  7. RNA chemistry and therapeutics.Nature reviews. Drug discovery · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Protonation of Borylated Carboxonium Derivative [2,6-BInternational journal of molecular sciences · 2022
    Article
  15. Primary Amine Nucleophilic Addition to NitriliumInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mariya A VorobyevaInstitute of Chemical Biology and Fundamental Medicine, Siberian Division of Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0001-5317-3288
Maya A DymovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Division of Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-7281-9096
Darya S NovopashinaInstitute of Chemical Biology and Fundamental Medicine, Siberian Division of Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0001-6082-6785
Elena V KuliginaInstitute of Chemical Biology and Fundamental Medicine, Siberian Division of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Valentina V TimoshenkoInstitute of Chemical Biology and Fundamental Medicine, Siberian Division of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Iaroslav A KolesnikovInstitute of Chemical Biology and Fundamental Medicine, Siberian Division of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Sergey Yu TaskaevBudker Institute of Nuclear Physics, Siberian Division of the Russian Academy of Sciences, 630090 Novosibirsk, Russia.ORCID 0000-0002-5313-2563
Vladimir A RichterInstitute of Chemical Biology and Fundamental Medicine, Siberian Division of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Alya G VenyaminovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Division of Russian Academy of Sciences, 630090 Novosibirsk, Russia.
Institute of Chemical Biology and Fundamental Medicine · RUNovosibirsk State University · RU

Funding

Russian Science Foundation 19-74-20127
6 · The paper itself

Abstract

Boron neutron capture therapy (BNCT) is a binary radiotherapeutic approach to the treatment of malignant tumors, especially glioblastoma, the most frequent and incurable brain tumor. For successful BNCT, a boron-containing therapeutic agent should provide selective and effective accumulation of

Indexed as

Aptamers, NucleotideBoronBoron CompoundsBoron Neutron Capture TherapyBrain NeoplasmsCell LineCell Line, TumorCell ProliferationGlioblastomaHumansIsotopesNeutronsAptamers, NucleotideBoronBoron-10Boron CompoundsdodecaborateIsotopesboron clustersboron neutron capture therapycancer treatmentcell-specific aptamersdrug deliveryhuman glioblastoma cells

Identifiers

PMID34298946
PMCPMC8307642
OpenAlexW3179595187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.