ArticleInternational journal of molecular sciences2021
Key Regulators of Sucrose Metabolism Identified through Comprehensive Comparative Transcriptome Analysis in Peanuts.
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 35 citations in OpenAlex.
- Cross-genera marker transferability, expression dynamics and in silico identification of rice seed size gene orthologs in contrasting groundnut genotypes.Molecular biology reports · 2026Article
- Mapping and Functional Characterization of Homologous Genes AhSUCA06 and AhSUCA16 Underlying Sucrose, Oil and Protein Contents in Peanut (Arachis hypogaea L.).Plant biotechnology journal · 2026Article
- Physiological and Transcriptomic Dissection of Inflorescence Degeneration inPlants (Basel, Switzerland) · 2026Article
- Coexpression network analysis reveals the genetic basis of divergent lipid and sugar accumulation in peanut (Food chemistry. Molecular sciences · 2026Article
- Sucrose as a key nutritional marker distinguishing vegetable and grain soybeans, regulated byHorticulture research · 2025Article
- Transcriptome analysis of genes and carbon partitioning pathways involved in high temperature stress resilience in groundnut (Arachis hypogaea L.).Scientific reports · 2025Article
- Exogenous Sucrose Improves the Vigor of Aged Safflower Seeds by Mediating Fatty Acid Metabolism and Glycometabolism.Plants (Basel, Switzerland) · 2025Article
- Integrative analysis of transcriptome and metabolome reveals molecular mechanisms of dynamic change of storage substances during dehydration and drying process in peanuts (Frontiers in plant science · 2025Article
- Article
- Optimizing Peanut (Plants (Basel, Switzerland) · 2024Review
- Detection of two homologous major QTLs and development of diagnostic molecular markers for sucrose content in peanut.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- HarnessingFrontiers in plant science · 2024Article
- Identification of a major QTL underlying sugar content in peanut kernels based on the RIL mapping population.Frontiers in plant science · 2024Article
- Omics-driven advances in the understanding of regulatory landscape of peanut seed development.Frontiers in plant science · 2024Review
- Global Transcriptome and Co-Expression Network Analyses Revealed Hub Genes Controlling Seed Size/Weight and/or Oil Content in Peanut.Plants (Basel, Switzerland) · 2023Article
- Identification of a stable major sucrose-related QTL and diagnostic marker for flavor improvement in peanut.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Comparative expression analysis ofPeerJ · 2023Article
- Identification of PeanutPlants (Basel, Switzerland) · 2022Article
- Sugar Metabolism and Transcriptome Analysis Reveal Key Sugar Transporters duringInternational journal of molecular sciences · 2022Article
- Mapping of a QTL associated with sucrose content in peanut kernels using BSA-seq.Frontiers in genetics · 2022Article
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Authors and funding
18 authors at 4 institutions in 3 countries.
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Abstract
Sucrose content is a crucial indicator of quality and flavor in peanut seed, and there is a lack of clarity on the molecular basis of sucrose metabolism in peanut seed. In this context, we performed a comprehensive comparative transcriptome study on the samples collected at seven seed development stages between a high-sucrose content variety (ICG 12625) and a low-sucrose content variety (Zhonghua 10). The transcriptome analysis identified a total of 8334 genes exhibiting significantly different abundances between the high- and low-sucrose varieties. We identified 28 differentially expressed genes (DEGs) involved in sucrose metabolism in peanut and 12 of these encoded sugars will eventually be exported transporters (SWEETs). The remaining 16 genes encoded enzymes, such as cell wall invertase (CWIN), vacuolar invertase (VIN), cytoplasmic invertase (CIN), cytosolic fructose-bisphosphate aldolase (FBA), cytosolic fructose-1,6-bisphosphate phosphatase (FBP), sucrose synthase (SUS), cytosolic phosphoglucose isomerase (PGI), hexokinase (HK), and sucrose-phosphate phosphatase (SPP). The weighted gene co-expression network analysis (WGCNA) identified seven genes encoding key enzymes (CIN, FBA, FBP, HK, and SPP), three SWEET genes, and 90 transcription factors (TFs) showing a high correlation with sucrose content. Furthermore, upon validation, six of these genes were successfully verified as exhibiting higher expression in high-sucrose recombinant inbred lines (RILs). Our study suggested the key roles of the high expression of SWEETs and enzymes in sucrose synthesis making the genotype ICG 12625 sucrose-rich. This study also provided insights into the molecular basis of sucrose metabolism during seed development and facilitated exploring key candidate genes and molecular breeding for sucrose content in peanuts.
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