ReviewInternational journal of molecular sciences2021
Smoking and Neuropsychiatric Disease-Associations and Underlying Mechanisms.
Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- P300 Event-Related Potentials as Cognitive Biomarkers in Neurological and Neuropsychiatric Disorders: A Systematic Review.Revista de neurologia · 2026Pooled it
- Smoking Initiation, Age at Onset of Symptoms and Suicide Attempts Among Patients With Bipolar Disorder: Comparisons With Non-Psychiatric Adults.Bipolar disorders · 2026Article
- Comorbidity and Familial Aggregation of Mood Disorders and Cigarette Smoking in a Controlled Family Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026Article
- Impact of Physical Activity on Smoking, Sleep Disorders, and Depression Among U.S. Adults.Health education & behavior : the official publication of the Society for Public Health Education · 2026Article
- A microglial LCN2-MC4R signaling axis drives silica-induced neuronal damage via C1q release.Journal of neuroinflammation · 2026Article
- A community screening tool for neuropsychiatric symptoms in the elderly: integrating cortisol, microbiome, and social factors with machine learning.Translational psychiatry · 2026Observational
- Article
- Vaping and mental health: A cross-sectional study among university students in Bangladesh.PloS one · 2026Article
- Acute aerobic exercise modulates sweetness-related food preference in individuals with nicotine dependence: the mediating role of prefrontal cortical activity.Frontiers in nutrition · 2026Article
- Comparative effects of alternate tobacco products and traditional tobacco smoking on various organ/systems: A guide to regulators and health policy makers.Toxicology reports · 2025Review
- Cardiovascular disease as a mediator in the relationship between lifestyle risk factors and cognitive outcomes: a scoping review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- An Association Analysis of Anxiety and Psoriasis: Based on the NHANES Database.Brain and behavior · 2025Article
- Article
- Disentangling the effects of nicotine versus non-nicotine constituents of tobacco smoke on major depressive disorder: A multivariable Mendelian randomisation study.Addiction (Abingdon, England) · 2025Article
- Risk factors of dementia in a cohort of individuals with mild cognitive impairment in the Italian Interceptor project.European journal of neurology · 2025Article
- Smoking and Obesity Interact to Adversely Affect Disease Progression and Cognitive Performance in Multiple Sclerosis.European journal of neurology · 2025Article
- Polytobacco usage and mental health among Malaysian secondary school-going adolescents: Findings from the national school-based study.Tobacco induced diseases · 2025Article
- Substance Use and Concurrent Disorders: Current Context and the Need for Treatment Integration.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2025Article
- Research Trends on Smoking, Depression, and Anxiety: Bibliometric Analysis.Consortium psychiatricum · 2025Review
- Associations of dietary biotin intake on anxiety and depression: findings from a population-based prospective cohort study.Frontiers in nutrition · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Despite extensive efforts to combat cigarette smoking/tobacco use, it still remains a leading cause of global morbidity and mortality, killing more than eight million people each year. While tobacco smoking is a major risk factor for non-communicable diseases related to the four main groups-cardiovascular disease, cancer, chronic lung disease, and diabetes-its impact on neuropsychiatric risk is rather elusive. The aim of this review article is to emphasize the importance of smoking as a potential risk factor for neuropsychiatric disease and to identify central pathophysiological mechanisms that may contribute to this relationship. There is strong evidence from epidemiological and experimental studies indicating that smoking may increase the risk of various neuropsychiatric diseases, such as dementia/cognitive decline, schizophrenia/psychosis, depression, anxiety disorder, and suicidal behavior induced by structural and functional alterations of the central nervous system, mainly centered on inflammatory and oxidative stress pathways. From a public health perspective, preventive measures and policies designed to counteract the global epidemic of smoking should necessarily include warnings and actions that address the risk of neuropsychiatric disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.