Evidence map›Paper›PMID 34298767›Full record

ArticleCancers2021

Radiation Pneumonitis in Thoracic Cancer Patients: Multi-Center Voxel-Based Analysis.

Giuseppe Palma, Serena Monti, Roberto Pacelli, Zhongxing Liao, Joseph O Deasy, Radhe Mohan, Laura Cella

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Integration of Dose Surface Maps and Genetic Data Identifies the Lower Posterior Rectum as a Key Region for Toxicity after Prostate Cancer Radiotherapy.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Image-based data mining applies to data collected from children.Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Giuseppe PalmaInstitute of Biostructures and Bioimaging, National Research Council, 80145 Napoli, Italy.
Serena MontiInstitute of Biostructures and Bioimaging, National Research Council, 80145 Napoli, Italy.ORCID 0000-0002-8777-7837
Roberto PacelliDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", 80131 Napoli, Italy.ORCID 0000-0002-2048-7675
Zhongxing LiaoDepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, TX 77030, USA.
Joseph O DeasyDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Radhe MohanDepartment of Radiation Physics, MD Anderson Cancer Center, Houston, TX 77030, USA.
Laura CellaInstitute of Biostructures and Bioimaging, National Research Council, 80145 Napoli, Italy.ORCID 0000-0003-0058-4029

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

This study investigates the dose-response patterns associated with radiation pneumonitis (RP) in patients treated for thoracic malignancies with different radiation modalities. To this end, voxel-based analysis (VBA) empowered by a novel strategy for the characterization of spatial properties of dose maps was applied. Data from 382 lung cancer and mediastinal lymphoma patients from three institutions treated with different radiation therapy (RT) techniques were analyzed. Each planning CT and biologically effective dose map (α/β = 3 Gy) was spatially normalized on a common anatomical reference. The VBA of local dose differences between patients with and without RP was performed and the clusters of voxels with dose differences that significantly correlated with RP at a

Indexed as

connectogramsprobabilistic independent component analysisradiation pneumonitisthoracic cancervoxel-based analysis

Identifiers

PMID34298767
PMCPMC8306650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.