Evidence map›Paper›PMID 34298729›Full record

ArticleCancers2021

Management of Patients with Pancreatic Ductal Adenocarcinoma in the Real-Life Setting: Lessons from the French National Hospital Database.

Christelle de la Fouchardière, Mustapha Adham, Anne-Marie Marion-Audibert, Antoine Duclos, Claude Darcha, Olivier Berthelet, Valérie Hervieu, Pascal Artru, Hélène Labrosse, Yohan Fayet and 13 more

Abstract read
In one paragraph

Article in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Christelle de la FouchardièreMedical Oncology Department, Centre Léon Bérard, 28 Rue Laennec, 69008 Lyon, France.ORCID 0000-0003-2291-5693
Mustapha AdhamSurgery Department, Hopital Edouard Herriot, 5 Place d'Arsonval, 69003 Lyon, France.
Anne-Marie Marion-AudibertGastroenterology and Hepatology, Clinique du Val d'Ouest, 39 Chemin de la Vernique, 69130 Ecully, France.
Antoine DuclosResearch on Healthcare Performance (RESHAPE), INSERM U1290, Université Claude Bernard Lyon 1, 69100 Lyon, France.
Claude DarchaPathology Department, CHU Estaing, 1 Rue Lucie et Raymond Aubrac, 63100 Clermont-Ferrand, France.
Olivier BertheletHépato-Gastro-Entérologie Department, Centre Hospitalier Métropole Savoie, Place Lucien Biset, 73011 Chambery, France.
Valérie HervieuPathology Department, Hopital Edouard Herriot, 5 Place d'Arsonval, 69003 Lyon, France.
Pascal ArtruGastroenterology Department, Hopital privé Jean Mermoz, 55 Avenue Jean Mermoz, 69008 Lyon, France.
Hélène LabrosseRéseau Régional de Cancérologie Auvergne-Rhône-Alpes (ONCO AURA), 60 Avenue Rockefeller, 69008 Lyon, France.
Yohan FayetResearch on Healthcare Performance (RESHAPE), INSERM U1290, Equipe EMS-Département de Sciences Humaines et Sociales, Centre Léon Bérard, 28 Rue Laennec, 69008 Lyon, France.ORCID 0000-0002-5664-4636
Bruno Ferroud-PlattetAgence Régionale de Santé (ARS) AuRA, 241 Rue Garibaldi, 69003 Lyon, France.
Bruno Aublet-CuvellierAgence Régionale de Santé (ARS) AuRA, 241 Rue Garibaldi, 69003 Lyon, France.
Georges ChambonURPS Infirmiers Libéraux Auvergne Rhône-Alpes, 21 Quai Antoine Riboud, 69002 Lyon, France.
Mathieu BaconnierHépatogastroentérology Department, Centre Hospitalier Annecy Genevois, 1 Avenue de l'Hôpital, 74370 Epagny Metz-Tessy, France.
Christine RebischungMedical Oncology Department, Medipole de Savoie, 300 Avenue des Massettes, 73190 Challes-les-Eaux, France.
Fadila FarsiRéseau Régional de Cancérologie Auvergne-Rhône-Alpes (ONCO AURA), 60 Avenue Rockefeller, 69008 Lyon, France.
Isabelle Ray-CoquardResearch on Healthcare Performance (RESHAPE), EA 7425, Centre Léon Bérard, 28 Rue Laennec, 69008 Lyon, France.ORCID 0000-0003-2472-8306
Charles MastierRadiology Department, Centre Léon Bérard, 28 Rue Laennec, 69008 Lyon, France.
Pierre-Jean TernamianURPS Médecins Liberaux AuRA, 20 Rue Barrier, 69006 Lyon, France.
Nicolas WillietHepatogastroenterology Department, CHU, Avenue Albert Raimond, 42270 Saint-Etienne, France.
Emmanuel BucDigestive and Hepatobiliary Surgery Department, CHU Estaing, 1 Rue Lucie et Raymond Aubrac, 63100 Clermont-Ferrand, France.
Thomas WalterMedical Oncology Department, Pavillons E-UJOMM, Hopital Edouard Herriot, 5 Place d'Arsonval, 69003 Lyon, France.ORCID 0000-0002-4199-4561
Andrée-Laure HerrAgence Régionale de Santé (ARS) AuRA, 241 Rue Garibaldi, 69003 Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) remains a major public health challenge, and faces disparities and delays in the diagnosis and access to care. Our purposes were to describe the medical path of PDAC patients in the real-life setting and evaluate the overall survival at 1 year. We used the national hospital discharge summaries database system to analyze the management of patients with newly diagnosed PDAC over the year 2016 in Auvergne-Rhône-Alpes region (AuRA) (France). A total of 1872 patients met inclusion criteria corresponding to an incidence of 22.6 per 100,000 person-year. Within the follow-up period, 353 (18.9%) were operated with a curative intent, 743 (39.7%) underwent chemo- and/or radiotherapy, and 776 (41.4%) did not receive any of these treatments. Less than half of patients were operated in a high-volume center, defined by more than 20 PDAC resections performed annually, mainly university hospitals. The 1-year survival rate was 47% in the overall population. This study highlights that a significant number of patients with PDAC are still operated in low-volume centers or do not receive any specific oncological treatment. A detailed analysis of the medical pathways is necessary in order to identify the medical and territorial determinants and their impact on the patient's outcome.

Indexed as

access to careadenocarcinomadisparitiesexpertisemedical pathwaypancreatic cancerpancreatic surgeryPDACreal-life datasurvival

Identifiers

PMID34298729
PMCPMC8306072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.