Evidence map›Paper›PMID 34298656›Full record

ReviewCancers2021

Translational Utility of Liquid Biopsies in Thyroid Cancer Management.

Ayanthi A Wijewardene, Marthe Chehade, Matti L Gild, Roderick J Clifton-Bligh, Martyn Bullock

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Review
  5. Article
  6. Liquid biopsy techniques and lung cancer: diagnosis, monitoring and evaluation.Journal of experimental & clinical cancer research : CR · 2024
    Review
  7. Article
  8. CTC, ctDNA, and Exosome in Thyroid Cancers: A Review.International journal of molecular sciences · 2023
    Review
  9. Review
  10. Review
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ayanthi A WijewardeneDepartment of Endocrinology, Royal North Shore Hospital, Sydney, NSW 2052, Australia.
Marthe ChehadeFaculty of Medicine and Health, University of Sydney, Sydney, NSW 2052, Australia.
Matti L GildDepartment of Endocrinology, Royal North Shore Hospital, Sydney, NSW 2052, Australia.
Roderick J Clifton-BlighDepartment of Endocrinology, Royal North Shore Hospital, Sydney, NSW 2052, Australia.
Martyn BullockDepartment of Endocrinology, Royal North Shore Hospital, Sydney, NSW 2052, Australia.ORCID 0000-0002-3740-5509
The University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liquid biopsies are a novel technique to assess for either circulating tumor cells (CTC) or circulating tumor DNA (ctDNA and microRNA (miRNA)) in peripheral blood samples of cancer patients. The diagnostic role of liquid biopsy in oncology has expanded in recent years, particularly in lung, colorectal and breast cancer. In thyroid cancer, the role of liquid biopsy in either diagnosis or prognosis is beginning to translate from the lab to the clinic. In this review, we describe the evolution of liquid biopsies in detecting CTC, ctDNA and miRNA in thyroid cancer patients, together with its limitations and future directions in clinical practice.

Indexed as

cell free DNA (cfDNA)circulating tumor DNA (ctDNA)liquid biopsymicroRNA (miRNA)thyroid cancer

Identifiers

PMID34298656
PMCPMC8306718
OpenAlexW3181687553

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.