Evidence map›Paper›PMID 34298424›Full record

ArticlePsychiatry research2021

Computational linguistic analysis applied to a semantic fluency task: A replication among first-episode psychosis patients with and without derailment and tangentiality.

Benson S Ku, Luca Pauselli, Michael A Covington, Michael T Compton

Abstract read
In one paragraph

Article in Psychiatry research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Trajectories through semantic spaces in schizophrenia and the relationship to ripple bursts.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Benson S KuDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Luca PauselliDepartment of Psychiatry, Icahn School of Medicine at Mount Sinai, Morningside/West Hospital Center, New York, NY, USA.
Michael A CovingtonCovington Innovations, Athens, GA, USA.
Michael T ComptonDepartment of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA; New York State Psychiatric Institute, New York, NY, USA. Electronic address: mtc2176@cumc.columbia.edu.

Funding

Emory Psychiatry Clinical Scientist Training Program (CSTP)R25MH101079 · NIMH · EMORY UNIVERSITY · PI GOLDSMITH, DAVID RYAN, MILLER, ANDREW H · 2014 to 2025
$1.9M
First-Episode Psychosis and Pre-Onset Cannabis UseR01MH081011 · NIMH · GEORGE WASHINGTON UNIVERSITY · PI MYERS, NEELY A · 2008 to 2012
$1.7M
Applying Computational Linguistics to Fundamental Components of SchizophreniaR21MH097999 · NIMH · GEORGE WASHINGTON UNIVERSITY · PI COMPTON, MICHAEL T · 2013 to 2014
$442k
NIMH NIH HHS R01 MH081011NIMH NIH HHS R21 MH097999NIMH NIH HHS R25 MH101079
6 · The paper itself

Abstract

Automated tools do not yet exist to measure formal thought disorder, including derailment and tangentiality, both of which can be subjectively rated using the Scale for the Assessment of Positive Symptoms after a clinical research interview. CoVec, a new automated tool, measures the semantic similarity among words averaged in a five- and ten-word window (Coherence-5 and Coherence-10, respectively). One prior report demonstrated that this tool was able to differentiate between patients with those types of thought disorder and patients without them (and controls). Here, we attempted a replication of the initial findings using data from a different sample of patients hospitalized for initial evaluation of first-episode psychosis. Participants were administered a semantic fluency task and the animal lists were analyzed with CoVec. In this study, we partially replicated the prior findings, showing that first-episode patients with derailment had significantly lower Coherence-5 and Coherence-10 compared with patients without derailment. Further research is warranted on this and other highly reliable and objective methods of detecting formal thought disorder through simple assessments such as semantic fluency tasks.

Indexed as

Psychotic DisordersSchizophreniaHumansLinguisticsSchizophrenic PsychologySemanticsDerailmentFirst-episode psychosisFormal thought disorderLoose associationsPsychosisSchizophreniaSemantic fluency tasks

Identifiers

PMID34298424
PMCPMC8719331

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.