Evidence map›Paper›PMID 34298058›Full record

ArticleThe Journal of investigative dermatology2022

Extended T-Cell Epitope Landscape in Merkel Cell Polyomavirus Large T and Small T Oncoproteins Identified Uniquely in Patients with Cancer.

Ulla Kring Hansen, Rikke Lyngaa, Dafina Ibrani, Candice Church, Monique Verhaegen, Andrzej Antoni Dlugosz, Jürgen Christian Becker, Per Thor Straten, Paul Nghiem, Sine Reker Hadrup

Open access · greenAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Tumor Antigens beyond the Human Exome.International journal of molecular sciences · 2024
    Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Ulla Kring HansenDepartment of Health Technology, Technical University of Denmark, Lyngby, Denmark.
Rikke LyngaaDepartment of Health Technology, Technical University of Denmark, Lyngby, Denmark.
Dafina IbraniDivision of Dermatology, Department of Medicine, University of Washington, Seattle, Washington, USA; Department of Laboratory Medicine & Pathology, University of Washington, Seattle, Washington, USA.
Candice ChurchDivision of Dermatology, Department of Medicine, University of Washington, Seattle, Washington, USA; Department of Laboratory Medicine & Pathology, University of Washington, Seattle, Washington, USA.
Monique VerhaegenDepartment of Dermatology, University of Michigan, Ann Arbor, Michigan, USA.
Andrzej Antoni DlugoszDepartment of Dermatology, University of Michigan, Ann Arbor, Michigan, USA; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA.
Jürgen Christian BeckerDepartment of Translational Skin Cancer Research, University Hospital Essen, Essen, Germany; German Cancer Consortium (DKTK), Essen, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Dermatology, University Hospital Essen, Essen, Germany.
Per Thor StratenNational Center for Cancer Immune Therapy, Copenhagen University Hospital, Herlev, Denmark.
Paul NghiemDivision of Dermatology, Department of Medicine, University of Washington, Seattle, Washington, USA; Department of Laboratory Medicine & Pathology, University of Washington, Seattle, Washington, USA; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA; Seattle Cancer Care Alliance Center, Seattle, Washington, USA.
Sine Reker HadrupDepartment of Health Technology, Technical University of Denmark, Lyngby, Denmark. Electronic address: sirha@dtu.dk.
Technical University of Denmark · DKUniversity of Michigan · USUniversity of Washington · USCopenhagen University Hospital · DKGerman Cancer Research Center · DESeattle Cancer Care Alliance · US

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
Understand & overcome resistance to PD-1P01CA225517 · NCI · UNIVERSITY OF WASHINGTON · PI PAUL NGHIEM · 2019 to 2026
$22.7M
Cell fate decisions in Merkel cell carcinoma initiation and maintenanceR01CA241947 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DLUGOSZ, ANDRZEJ A., VERHAEGEN, MONIQUE ELISE · 2020 to 2024
$2.6M
Merkel cell polyomavirus T antigens in tumorigenesisR01CA189352 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DLUGOSZ, ANDRZEJ A., VERHAEGEN, MONIQUE ELISE · 2015 to 2019
$1.8M
NCI NIH HHS P01 CA225517NCI NIH HHS P30 CA015704NCI NIH HHS R01 CA189352NCI NIH HHS R01 CA241947
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overAntigens, Viral, TumorCarcinoma, Merkel CellCD8-Positive T-LymphocytesCells, CulturedEpitope MappingEpitopes, T-LymphocyteFemaleHLA AntigensHumansImmunologic SurveillanceLymphocyte ActivationMaleMerkel cell polyomavirusAntigens, Viral, TumorEpitopes, T-LymphocyteHLA AntigensPeptides

Identifiers

PMID34298058
PMCPMC9413685
OpenAlexW3185079198

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.