Evidence map›Paper›PMID 34298043›Full record

ArticleDiabetes research and clinical practice2021

Diabetes mellitus as a risk factor for SARS-CoV-2 test positivity in Mexico: A propensity score matched study.

Jacqueline A Seiglie, Edson Serván-Mori, Jennifer Manne-Goehler, James B Meigs, J Jaime Miranda, Sandra G Sosa-Rubí, Omar Silverman-Retana, Deborah J Wexler, Veronika J Wirtz

Abstract read
In one paragraph

Article in Diabetes research and clinical practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Jacqueline A SeiglieDiabetes Unit, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Edson Serván-MoriCenter for Health Systems Research, National Institute of Public Health, Cuernavaca, Mexico. Electronic address: eservan@insp.mx.
Jennifer Manne-GoehlerDivision of Infectious Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
James B MeigsDepartment of General Internal Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
J Jaime MirandaCRONICAS Center of Excellence in Chronic Diseases, Universidad Peruana Cayetano Heredia, Lima, Peru; The George Institute for Global Health, Sydney, Australia.
Sandra G Sosa-RubíCenter for Health Systems Research, National Institute of Public Health, Cuernavaca, Mexico.
Omar Silverman-RetanaSteno Diabetes Center Aarhus, Aarhus University Hospital, Aarhus, Denmark.
Deborah J WexlerDiabetes Unit, Massachusetts General Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA.
Veronika J WirtzDepartment of Global Health, Boston University School of Public Health, Boston, MA, USA.

Funding

TRAINING PROGRAM IN ENDOCRINOLOGY AND DIABETEST32DK007028 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Karen K Miller · 1986 to 2026
$18.5M
Institutional Career Development CoreKL2TR002542 · NCATS · HARVARD MEDICAL SCHOOL · PI BREDELLA, MIRIAM ANTOINETTE, RUTKOVE, SEWARD B. · 2018 to 2022
$8.7M
NCATS NIH HHS KL2 TR002542NIDDK NIH HHS T32 DK007028
6 · The paper itself

Abstract

aimsWe sought to investigate whether individuals with diabetes have a higher likelihood of testing positive for SARS-CoV-2, as a proxy for infection risk, than individuals without diabetes.

methodsWe conducted a cross-sectional study of publicly available data among a Mexican population, totaling 2,314,022 adults ≥ 18 years who underwent SARS-CoV-2 testing between March 1 and December 20, 2020. We used 1:1 nearest neighborhood propensity score matching by diabetes status to account for confounding among those with and without diabetes.

resultsIn the overall study population, 1,057,779 (45.7%) individuals tested positive for SARS-CoV-2 and 270,486 (11.7%) self-reported diabetes. After propensity score matching, patient characteristics were well-balanced, with 150,487 patients in the diabetes group (mean [SD] age 55.9 [12.7] years; 51.3% women) and 150,487 patients in the no diabetes group (55.5 [13.3] years; 50.3% women). The strictest matching algorithm (1:1 nearest neighbor) showed that compared to individuals without diabetes, having diabetes was associated with 9.0% higher odds of having a positive SARS-CoV-2 test (OR 1.09 [95% CI: 1.08-1.10]).

conclusionsPresence of diabetes was associated with higher odds of testing positive for SARS-CoV-2, which could have important implications for risk mitigation efforts for people with diabetes at risk of SARS-CoV-2 infection.

Indexed as

COVID-19Diabetes MellitusAdolescentAdultAgedCOVID-19 TestingCross-Sectional StudiesFemaleHumansMaleMexicoMiddle AgedPropensity ScoreRisk FactorsSARS-CoV-2Young Adult

Identifiers

PMID34298043
PMCPMC8331361

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.