Evidence map›Paper›PMID 34297964›Full record

ArticleBiophysical journal2021

MitoWave: Spatiotemporal analysis of mitochondrial membrane potential fluctuations during I/R.

Deepthi Ashok, Brian O'Rourke

Open access · greenAbstract read
In one paragraph

Article in Biophysical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Deepthi AshokThe Johns Hopkins University, Division of Cardiology, Department of Medicine, Baltimore, Maryland.
Brian O'RourkeThe Johns Hopkins University, Division of Cardiology, Department of Medicine, Baltimore, Maryland. Electronic address: bor@jhmi.edu.
Johns Hopkins University · US

Funding

PATHOPHYSIOLOGY OF MYOCARDIAL DISEASEST32HL007227 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI Chulan Kwon, WENDY S POST · 1985 to 2026
$21.2M
Targeting Metabo-Redox Network Vulnerability in Heart Failure and Sudden DeathR01HL134821 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI FOSTER, D BRIAN, O'ROURKE, BRIAN · 2018 to 2021
$2.1M
Molecular Determinants of Mitochondrial Instability and ArrhythmiasR01HL137259 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI AKAR, FADI GABRIEL, O'ROURKE, BRIAN · 2017 to 2020
$2.0M
Olympus FluoView3000RS Confocal MicroscopeS10OD025244 · OD · JOHNS HOPKINS UNIVERSITY · PI O'ROURKE, BRIAN · 2018 to 2018
$448k
Heart Failure Therapy by CRISPR-Mediated Upregulation of Mitochondrial BiogenesisF31HL134198 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI ASHOK, DEEPTHI · 2016 to 2018
$132k
NHLBI NIH HHS F31 HL134198NHLBI NIH HHS R01 HL134821NHLBI NIH HHS R01 HL137259NHLBI NIH HHS T32 HL007227NIH HHS S10 OD025244
6 · The paper itself

Abstract

Mitochondria exhibit unstable inner membrane potentials (ΔΨ

Indexed as

IschemiaMyocytes, CardiacAnimalsMembrane Potential, MitochondrialMiceMitochondria, HeartReperfusionSpatio-Temporal Analysis

Identifiers

PMID34297964
PMCPMC8392080
OpenAlexW3185138079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.