Evidence map›Paper›PMID 34297747›Full record

ArticlePloS one2021

The synchronicity of COVID-19 disparities: Statewide epidemiologic trends in SARS-CoV-2 morbidity, hospitalization, and mortality among racial minorities and in rural America.

Brian E Dixon, Shaun J Grannis, Lauren R Lembcke, Nimish Valvi, Anna R Roberts, Peter J Embi

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Prediction models for COVID-19 disease outcomes.Emerging microbes & infections · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Using wastewater to overcome health disparities among rural residents.Geoforum; journal of physical, human, and regional geosciences · 2023
    Article
  11. Article
  12. Higher hospitalization and mortality rates among SARS-CoV-2-infected persons in rural America.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Epidemiological Features of COVID-19 in Makkah City: A Retrospective Data Analysis.Computational and mathematical methods in medicine · 2022
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brian E DixonDepartment of Epidemiology, Fairbanks School of Public Health, Indiana University, Bloomington, Indiana, United States of America.ORCID 0000-0002-1121-0607
Shaun J GrannisCenter for Biomedical Informatics, Regenstrief Institute, Indianapolis, Indiana, United States of America.
Lauren R LembckeResearch Data Services, Regenstrief Institute, Indianapolis, Indiana, United States of America.
Nimish ValviCenter for Biomedical Informatics, Regenstrief Institute, Indianapolis, Indiana, United States of America.
Anna R RobertsResearch Data Services, Regenstrief Institute, Indianapolis, Indiana, United States of America.
Peter J EmbiCenter for Biomedical Informatics, Regenstrief Institute, Indianapolis, Indiana, United States of America.ORCID 0000-0002-7733-0847

Funding

Exploring the Utilization of and Outcomes from Health Information Exchange in Emergency SettingsR21HS025502 · AHRQ · INDIANA UNIVERSITY INDIANAPOLIS · PI DIXON, BRIAN E. · 2017 to 2018
$297k
AHRQ HHS R21 HS025502
6 · The paper itself

Abstract

backgroundEarly studies on COVID-19 identified unequal patterns in hospitalization and mortality in urban environments for racial and ethnic minorities. These studies were primarily single center observational studies conducted within the first few weeks or months of the pandemic. We sought to examine trends in COVID-19 morbidity, hospitalization, and mortality over time for minority and rural populations, especially during the U.S. fall surge.

methodsData were extracted from a statewide cohort of all adult residents in Indiana tested for SARS-CoV-2 infection between March 1 and December 31, 2020, linked to electronic health records. Primary measures were per capita rates of infection, hospitalization, and death. Age adjusted rates were calculated for multiple time periods corresponding to public health mitigation efforts. Comparisons across time within groups were compared using ANOVA.

resultsMorbidity and mortality increased over time with notable differences among sub-populations. Initially, hospitalization rates among racial minorities were 3-4 times higher than whites, and mortality rates among urban residents were twice those of rural residents. By fall 2020, hospitalization and mortality rates in rural areas surpassed those of urban areas, and gaps between black/brown and white populations narrowed. Changes across time among demographic groups was significant for morbidity and hospitalization. Cumulative morbidity and mortality were highest among minority groups and in rural communities.

conclusionsThe synchronicity of disparities in COVID-19 by race and geography suggests that health officials should explicitly measure disparities and adjust mitigation as well as vaccination strategies to protect those sub-populations with greater disease burden.

Indexed as

COVID-19EthnicityHealth Status DisparitiesHospitalizationMinority GroupsRural PopulationSARS-CoV-2AdolescentAdultAgedAged, 80 and overFemaleHumansIndianaMaleMiddle Aged

Identifiers

PMID34297747
PMCPMC8301667

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.