Evidence map›Paper›PMID 34297334›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2021

Protection against UVB deleterious skin effects in a mouse model: effect of a topical emulsion containing Cordia verbenacea extract.

Cristina P B Melo, Priscila Saito, David L Vale, Camilla C A Rodrigues, Ingrid C Pinto, Renata M Martinez, Julia R Bezerra, Marcela M Baracat, Waldiceu A Verri, Yris Maria Fonseca-Bazzo and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Cristina P B MeloPharmaceutical Sciences Department, State University of Londrina-UEL, University Hospital, Avenida Robert Koch, 60, Vila Operária, Londrina, Paraná, CEP 86039-440, Brazil.ORCID http://orcid.org/0000-0003-1445-7637
Priscila SaitoPharmaceutical Sciences Department, State University of Londrina-UEL, University Hospital, Avenida Robert Koch, 60, Vila Operária, Londrina, Paraná, CEP 86039-440, Brazil.ORCID http://orcid.org/0000-0002-8002-0559
David L ValePharmaceutical Sciences Department, State University of Londrina-UEL, University Hospital, Avenida Robert Koch, 60, Vila Operária, Londrina, Paraná, CEP 86039-440, Brazil.ORCID http://orcid.org/0000-0002-8995-7815
Camilla C A RodriguesPharmaceutical Sciences Department, State University of Londrina-UEL, University Hospital, Avenida Robert Koch, 60, Vila Operária, Londrina, Paraná, CEP 86039-440, Brazil.ORCID http://orcid.org/0000-0002-2268-0583
Ingrid C PintoPharmaceutical Sciences Department, State University of Londrina-UEL, University Hospital, Avenida Robert Koch, 60, Vila Operária, Londrina, Paraná, CEP 86039-440, Brazil.ORCID http://orcid.org/0000-0002-5983-0960
Renata M MartinezPharmaceutical Sciences Department, State University of Londrina-UEL, University Hospital, Avenida Robert Koch, 60, Vila Operária, Londrina, Paraná, CEP 86039-440, Brazil.ORCID http://orcid.org/0000-0003-1096-0876
Julia R BezerraPharmaceutical Sciences Department, State University of Londrina-UEL, University Hospital, Avenida Robert Koch, 60, Vila Operária, Londrina, Paraná, CEP 86039-440, Brazil.
Marcela M BaracatPharmaceutical Sciences Department, State University of Londrina-UEL, University Hospital, Avenida Robert Koch, 60, Vila Operária, Londrina, Paraná, CEP 86039-440, Brazil.ORCID http://orcid.org/0000-0002-7109-7191
Waldiceu A VerriPathological Sciences Department, State University of Londrina-UEL, Km 380 Celso Garcia Cid Hwy (PR-445), P.O. Box 10.011, Londrina, Paraná, 86057-970, Brazil.ORCID http://orcid.org/0000-0003-2756-9283
Yris Maria Fonseca-BazzoQuality Control Laboratory, School of Health Sciences, University of Brasilia, Campus Darcy Ribeiro, Asa Norte, Brasília, DF, CEP 70910-900, Brazil.ORCID http://orcid.org/0000-0002-1230-3207
Sandra R GeorgettiPharmaceutical Sciences Department, State University of Londrina-UEL, University Hospital, Avenida Robert Koch, 60, Vila Operária, Londrina, Paraná, CEP 86039-440, Brazil.ORCID http://orcid.org/0000-0003-2580-8762
Rubia CasagrandePharmaceutical Sciences Department, State University of Londrina-UEL, University Hospital, Avenida Robert Koch, 60, Vila Operária, Londrina, Paraná, CEP 86039-440, Brazil. rubiacasa@yahoo.com.br.ORCID http://orcid.org/0000-0002-2296-1668
Universidade Estadual de Londrina · BRUniversidade de Brasília · BR

Funding

CAPES (BR) 001CNPq (BR) 2017-2CNPq (BR) 307186CNPq (BR) 307852, 2019-9PRONEX grant supported by SETI/Fundação Araucária and MCTI/CNPq, and Governo do Estado do Paraná (BR) 2/46843, 2016SETI/Fundação Araucária (PR, Brazil) PBA 014, protocol 47396, 2017
6 · The paper itself

Abstract

Cordia verbenacea DC (Boraginaceae) is a flowering shrub found along the Brazilian Atlantic Forest, Brazilian coast, and low areas of the Amazon. The crude extract of its leaves is widely used in Brazilian folk medicine as an anti-inflammatory, both topically and orally. The aim of this study is to evaluate the activity of C. verbenacea ethanolic leaves extract (CVE) against UVB-triggered cutaneous inflammation and oxidative damage in hairless mice. CVE treatment recovered cutaneous antioxidant capacity demonstrated by scavenging ABTS

Indexed as

CordiaMice, HairlessPlant ExtractsSkinUltraviolet RaysAdministration, TopicalAnimalsAntioxidantsDisease Models, AnimalEmulsionsMiceOxidative StressPlant LeavesAntioxidantsEmulsionsPlant ExtractsCOX-2GSHInflammationOxidative stressRadical scavengerSunburn cells

Identifiers

PMID34297334
OpenAlexW3185139388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.