Evidence map›Paper›PMID 34297305›Full record

ArticleInternational ophthalmology2021

Clinical profile and response to steroids in post-fever retinitis: a nine-year experience from a referral institute in the rural hinterland of Central India.

Pratik Shenoy, Gaurav Mohan Kohli, Aarti Kerketta, Parul Pathak, Sachin Shetty, Pradip Barde, Tapas Chakma, Alok Sen

Abstract read
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In one paragraph

Article in International ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Epidemic retinitis during the COVID-19 pandemic.Indian journal of ophthalmology · 2023
    Observational
  2. Epidemic retinitis during pregnancy.Indian journal of ophthalmology · 2023
    Observational
  3. Monitoring Weil-Felix test in epidemic retinitis.Indian journal of ophthalmology · 2023
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Pratik ShenoyDepartment of Vitreo-Retina and Uveitis. Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, 210204, India.
Gaurav Mohan KohliDepartment of Vitreo-Retina and Uveitis. Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, 210204, India.
Aarti KerkettaDepartment of Vitreo-Retina and Uveitis. Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, 210204, India.
Parul PathakDepartment of Vitreo-Retina and Uveitis. Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, 210204, India.
Sachin ShettyDepartment of Vitreo-Retina and Uveitis. Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, 210204, India.
Pradip BardeICMR-National Institute of Research in Tribal Health, Jabalpur, Madhya Pradesh, 482003, India.
Tapas ChakmaICMR-National Institute of Research in Tribal Health, Jabalpur, Madhya Pradesh, 482003, India.
Alok SenDepartment of Vitreo-Retina and Uveitis. Shri Sadguru Seva Sangh Trust, Sadguru Netra Chikitsalaya, Chitrakoot, Madhya Pradesh, 210204, India. draloksen@gmail.com.ORCID http://orcid.org/0000-0003-2374-4187
National Institute for Research in Tribal Health · INInstitute of Medical Sciences · INMahatma Gandhi Chitrakoot Gramodaya Vishwavidyalaya · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the demographics, clinical features, and treatment outcomes with systemic steroids in eyes presenting with post-fever retinitis (PFR) from Central India.

methodsSingle-center, retrospective analysis of 147 eyes of 98 PFR cases between 2011 and 2019.

resultsMean age of the study cohort was 33.46 ± 12.76 years, with 72 males and 26 females. The mean interval between the onset of fever and the diminution of vision was 21.10 ± 13.54 days (range 0-60 days). The number of PFR cases increased over the nine years with 89 cases (90.1%) presenting during winters. Unilateral involvement was seen in 49 cases, while 49 had bilateral involvement. Clinical characteristics included: multifocal retinitis (n = 122; 61.2%), hemorrhages (n = 132; 89.8%), disc edema (n = 57; 38.8%), anterior chamber reaction (n = 28; 19%), and vitritis (n = 103; 70.1%). Treatment included intravenous followed by oral steroids in 70 patients and oral steroids exclusively in 23; five patients denied treatment. The visual acuity improved from 1.09 ± 0.52 LogMAR to 0.29 ± 0.42 LogMAR (p < 0.05).

conclusionThere has been an increase in the prevalence of PFR cases over the last decade with clustering during the winters. Multifocal retinitis, retinal hemorrhages, and vitritis were the most common clinical findings in our series. The retinitis resolved with improvement in vision following steroid therapy in all eyes.

Indexed as

RetinitisAdultFemaleHumansIndiaMaleMiddle AgedReferral and ConsultationRetrospective StudiesSteroidsYoung AdultSteroidsEpidemic retinitisImmune retinitisPost-fever retinitisRetinitisSteroids

Identifiers

PMID34297305
OpenAlexW3184909489

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.