Evidence map›Paper›PMID 34297142›Full record

ReviewDer Nervenarzt2021

[Multiple sclerosis treatment consensus group (MSTCG): position paper on disease-modifying treatment of multiple sclerosis 2021 (white paper)].

Heinz Wiendl, Ralf Gold, Thomas Berger, Tobias Derfuss, Ralf Linker, Mathias Mäurer, Martin Stangel, Orhan Aktas, Karl Baum, Martin Berghoff and 38 more

Abstract readReviewConsensus Statement
In one paragraph

Review in Der Nervenarzt, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. German translation, cultural adaptation for Austria, and validation of the Neurological Sleep Index-Multiple Sclerosis.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  3. Article
  4. Observational
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

48 authors.

Heinz WiendlKlinik für Neurologie mit Institut für Translationale Neurologie, Universitätsklinikum Münster, Westfälische Wilhelms-Universität Münster, Albert-Schweitzer-Campus 1, Gebäude A1, 48149, Münster, Deutschland. wiendl@uni-muenster.de.
Ralf GoldSteuerungsgruppe der MSTKG, Münster, Deutschland. ralf.gold@rub.de.
Thomas BergerSteuerungsgruppe der MSTKG, Münster, Deutschland.
Tobias DerfussSteuerungsgruppe der MSTKG, Münster, Deutschland.
Ralf LinkerSteuerungsgruppe der MSTKG, Münster, Deutschland.
Mathias MäurerSteuerungsgruppe der MSTKG, Münster, Deutschland.
Martin StangelSteuerungsgruppe der MSTKG, Münster, Deutschland.
Orhan AktasMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Karl BaumMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Martin BerghoffMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Stefan BittnerMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Andrew ChanMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Adam CzaplinskiMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Florian DeisenhammerMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Franziska Di PauliMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Renaud Du PasquierMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Christian EnzingerMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Elisabeth FertlMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Achim GassMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Klaus GehringMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Claudio GobbiMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Norbert GoebelsMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Michael GugerMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Aiden HaghikiaMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Hans-Peter HartungMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Fedor HeidenreichMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Olaf HoffmannMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Zoë R HunterKlinik für Neurologie mit Institut für Translationale Neurologie, Universitätsklinikum Münster, Münster, Deutschland.
Boris KallmannMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Christoph KleinschnitzMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Luisa KlotzMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Verena LeussinkMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Fritz LeutmezerMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Volker LimmrothMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Jan D LünemannMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Andreas LutterottiMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Sven G MeuthMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Uta Meyding-LamadéMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Michael PlattenMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Peter RieckmannMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Stephan SchmidtMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Hayrettin TumaniMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Martin S WeberMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Frank WeberMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Uwe K ZettlMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Tjalf ZiemssenMultiple Sklerose Therapie Konsensus Gruppe (MSTKG), Münster, Deutschland.
Frauke ZippSteuerungsgruppe der MSTKG, Münster, Deutschland.
die Multiple Sklerose Therapie Konsensus Gruppe (MSTKG)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis is a complex, autoimmune-mediated disease of the central nervous system characterized by inflammatory demyelination and axonal/neuronal damage. The approval of various disease-modifying therapies and our increased understanding of disease mechanisms and evolution in recent years have significantly changed the prognosis and course of the disease. This update of the Multiple Sclerosis Therapy Consensus Group treatment recommendation focuses on the most important recommendations for disease-modifying therapies of multiple sclerosis in 2021. Our recommendations are based on current scientific evidence and apply to those medications approved in wide parts of Europe, particularly German-speaking countries (Germany, Austria, Switzerland).

Indexed as

Multiple SclerosisCentral Nervous SystemConsensusEuropeGermanyHumansAutoimmune-mediated diseaseEarly therapeutic interventionGuidelineImmunotherapyTreatment recommendation

Identifiers

PMID34297142
PMCPMC8300076

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.