Evidence map›Paper›PMID 34297135›Full record

ReviewThe Journal of membrane biology2021

The Na/K-ATPase Signaling and SGLT2 Inhibitor-Mediated Cardiorenal Protection: A Crossed Road?

Jiang Liu, Jiang Tian, Komal Sodhi, Joseph I Shapiro

Open access · hybridAbstract readReview
In one paragraph

Review in The Journal of membrane biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jiang LiuDepartment of Biomedical Sciences, JCE School of Medicine, Marshall University, Huntington, WV, USA. liuj@marshall.edu.
Jiang TianDepartment of Biomedical Sciences, JCE School of Medicine, Marshall University, Huntington, WV, USA.
Komal SodhiDepartment of Surgery, JCE School of Medicine, Marshall University, Huntington, WV, USA.
Joseph I ShapiroDepartments of Medicine, JCE School of Medicine, Marshall University, Huntington, WV, USA.
Marshall University · US

Funding

CORAL: Clinical Coordinating CenterU01HL071556 · NHLBI · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · PI COOPER, CHRISTOPHER J · 2004 to 2013
$19.3M
Role of Adipocyte Na/K-ATPase Signaling in the Development and Progression of Uremic Cardiomyopathy By Altering Adipocyte PhenotypeR15HL150721 · NHLBI · MARSHALL UNIVERSITY · PI SODHI, KOMAL · 2020 to 2020
$444k
The Role of Oxidative Signaling through Na/K-ATPase in PNx-induced AnemiaR15HL164682 · NHLBI · MARSHALL UNIVERSITY · PI LIU, JIANG · 2022 to 2022
$444k
The Role of Oxidative Signaling through Na/K-ATPase in Salt-Sensitive HypertensionR15DK106666 · NIDDK · MARSHALL UNIVERSITY · PI LIU, JIANG · 2016 to 2016
$435k
NHLBI NIH HHS R15 HL150721NHLBI NIH HHS R15 HL164682NHLBI NIH HHS U01 HL071556NIDDK NIH HHS R15 DK106666
6 · The paper itself

Abstract

In different large-scale clinic outcome trials, sodium (Na

Indexed as

Signal TransductionGlucoseHumansKidneySodiumSodium-Glucose Transporter 2 InhibitorsSodium-Potassium-Exchanging ATPaseGlucoseSodiumSodium-Glucose Transporter 2 InhibitorsSodium-Potassium-Exchanging ATPaseNa/K-ATPaseROSSGLT inhibitorSignaling

Identifiers

PMID34297135
PMCPMC8595165
OpenAlexW3183471185

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.