ArticleAnnals of surgical oncology2022
Phyllodes Tumors: A Scoping Review of the Literature.
Article in Annals of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 50 citations in OpenAlex.
- Incidental colon adenocarcinoma in a patient with an Exophytic breast mass.Oxford medical case reports · 2026Article
- Contemporary management of phyllodes tumours of the breast: recommendations from the UK Association of Breast Surgery.The British journal of surgery · 2025Article
- Hierarchical diagnosis of breast phyllodes tumors enabled by deep learning of ultrasound images: a retrospective multi-center study.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025Article
- Phyllodes Tumor of the Breast: A Case Report Regarding the Importance of Fast Interdisciplinary Management.Reports (MDPI) · 2025Article
- Borderline Phyllodes Breast Tumors: A Comprehensive Review of Recurrence, Histopathological Characteristics, and Treatment Modalities.Current oncology (Toronto, Ont.) · 2025Review
- From Fibroadenoma to Phyllodes Tumor: Case Analysis of Borderline and Giant Breast Tumors with Literature Review.Acta medica Lituanic · 2025Article
- Management of malignant breast phyllodes tumor with rib invasion during pregnancy: a rare case report and literature review.Frontiers in oncology · 2025Article
- Intra-tumor and peritumoral radiomics and deep learning based on ultrasound for differentiating fibroadenoma and phyllodes tumor: a multicenter study.Frontiers in oncology · 2025Article
- Surgical treatment of giant phyllodes tumors of the breast: a series of rare cases.Frontiers in oncology · 2025Article
- Exploring the clinical and histopathological characteristics on breast phyllodes tumors predictors and prognosis in a real world.Frontiers in oncology · 2025Article
- Clinicopathological features and risk factors for local recurrence of breast phyllodes tumors: a dual-center, 12-year, retrospective study.Frontiers in oncology · 2025Article
- Evaluation of the Clinicopathological Features Associated With Malignancy of Phyllodes Tumor of the Breast.Cureus · 2024Article
- Prognostic value of Ki67 in phyllodes tumor of the breast: A systematic review and meta‑analysis.Experimental and therapeutic medicine · 2024Article
- Article
- The treatment process of a giant phyllodes tumor of the breast: a case report and review of the literature.Frontiers in oncology · 2024Article
- Primary breast sarcomas: A 13 case-series study treated in university hospital in central Tunisia over a 25-year period.Breast disease · 2024Article
- Management of Benign Phyllodes Tumors: A Dutch Population-Based Retrospective Cohort Between 1989 and 2022.Annals of surgical oncology · 2023Article
- ASO Author Reflections: Development of Canadian National Consensus Statements on Phyllodes Tumors of the Breast.Annals of surgical oncology · 2023Article
- Phyllodes Tumors of the Breast: Canadian National Consensus Document Using Modified Delphi Methodology.Annals of surgical oncology · 2023Review
- Clinical perspectives and outcomes of the giant breast phyllodes tumor and sarcoma: a real-world retrospective study.BMC cancer · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePhyllodes tumors are rare tumors of the breast, with most literature being retrospective with limited guidelines on the management of these patients. Scoping review was performed to highlight themes and gaps in the available literature.
methodsA scoping review of the literature was performed as per PRISMA-ScR guidelines with titles, abstracts, and full texts reviewed in duplicate. Data were abstracted and summarized in categories of diagnostics, surgical management, adjuvant therapies, treatment of recurrence, and surveillance. Quality assessment was performed for each paper.
resultsThe search identified 4498 references, 434 full-text papers were reviewed, and 183 papers were included. Ultrasound, magnetic resonance imaging, and core needle biopsy are valuable preoperative diagnostics tools. Pathology reporting should include stromal overgrowth, stromal cellularity, nuclear atypia, mitotic rate, borders, and presence of heterologous elements. Ki67 may have a role in grading and prognosticating. Breast conservation is safe in all grades of phyllodes but may be associated with increased local recurrence in malignant phyllodes. Surgical margins should depend on grade. Axillary node positivity rate is very low, even with clinically enlarged lymph nodes. Adjuvant radiation is a useful tool to decrease local recurrence in malignant phyllodes tumors, tumors > 5 cm, age < 45 years, close margins, and breast conservation. There is no evidence supporting adjuvant chemotherapy. Recurrence can be managed with repeat wide excision; however, mastectomy is associated with lower re-recurrence. Surveillance protocols are variable in the literature.
conclusionsThere is heterogeneity in the literature on phyllodes tumors. Consensus guidelines based on the literature will help provide evidence-based care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.