Evidence map›Paper›PMID 34296321›Full record

ArticleDiabetologia2021

Association of maternal vitamin B

Ponnusamy Saravanan, Nithya Sukumar, Antonysunil Adaikalakoteswari, Ilona Goljan, Hema Venkataraman, Amitha Gopinath, Christos Bagias, Chittaranjan S Yajnik, Nigel Stallard, Yonas Ghebremichael-Weldeselassie and 1 more

Registry-linked trialOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in Diabetologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03008824 (Micronutrients in Pregnancy as a Risk Factor for Diabetes and Effects on Mother and Baby), which is not on this map. Cited by 48 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 5 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03008824 unknown statusnot on this map

Micronutrients in Pregnancy as a Risk Factor for Diabetes and Effects on Mother and Baby: PRiDE Study

TypeobservationalSponsorUniversity of WarwickRan2012 to 2018Enrolled4,500ConditionsGestational Diabetes
3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 5 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Review
  8. Preconception Perceptions, Knowledge and Behaviours of Women With Gestational Diabetes Mellitus: A Qualitative Study.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  9. Review
  10. Observational
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Vitamin BClinical nutrition ESPEN · 2025
    Observational
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Ponnusamy SaravananDivision of Health Sciences, Warwick Medical School, Gibbet Hill, University of Warwick, Warwick, Coventry, UK. p.saravanan@warwick.ac.uk.ORCID 0000-0002-9566-2626
Nithya SukumarDivision of Health Sciences, Warwick Medical School, Gibbet Hill, University of Warwick, Warwick, Coventry, UK.ORCID 0000-0002-8549-2061
Antonysunil AdaikalakoteswariDivision of Health Sciences, Warwick Medical School, Gibbet Hill, University of Warwick, Warwick, Coventry, UK.ORCID 0000-0003-2974-3388
Ilona GoljanAcademic Department of Diabetes, Endocrinology and Metabolism, George Eliot Hospital, Nuneaton, UK.
Hema VenkataramanDivision of Health Sciences, Warwick Medical School, Gibbet Hill, University of Warwick, Warwick, Coventry, UK.ORCID 0000-0002-3497-3885
Amitha GopinathAcademic Department of Diabetes, Endocrinology and Metabolism, George Eliot Hospital, Nuneaton, UK.
Christos BagiasDivision of Health Sciences, Warwick Medical School, Gibbet Hill, University of Warwick, Warwick, Coventry, UK.ORCID 0000-0002-1703-4325
Chittaranjan S YajnikDiabetes Unit, KEM Hospital & Research Centre, Pune, India.ORCID 0000-0002-2911-2378
Nigel StallardDivision of Health Sciences, Warwick Medical School, Gibbet Hill, University of Warwick, Warwick, Coventry, UK.ORCID 0000-0001-7781-1512
Yonas Ghebremichael-WeldeselassieDivision of Health Sciences, Warwick Medical School, Gibbet Hill, University of Warwick, Warwick, Coventry, UK.ORCID 0000-0003-4961-5041
Caroline H D FallMRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.ORCID 0000-0003-4402-5552
George Eliot Hospital · GBUniversity of Warwick · GBMRC Lifecourse Epidemiology Unit · GBThe Open University · GB

Funding

Medical Research Council MR/J000094/1
6 · The paper itself

Abstract

aims/hypothesisThe prevalence of gestational diabetes mellitus (GDM) is increasing worldwide in all ethnic groups. Low vitamin B

methodsThis was a prospective, multi-centre, multi-ethnic cohort study (n = 4746) in the UK. Participants who were eligible to be selectively screened as per the National Institute for Health and Care Excellence (NICE) criteria were included in the study.

resultsGDM prevalence was 12.5% by NICE and 14.7% by International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria. Folate deficiency (1.3%) was rare but B CONCLUSIONS/

interpretationB

trial registrationClinicalTrials.gov NCT03008824.

Indexed as

AdolescentAdultBlood GlucoseDiabetes, GestationalFemaleFolic AcidFolic Acid DeficiencyGestational AgeHeart DiseasesHumansMiddle AgedPregnancyPregnancy in DiabeticsPrevalenceProspective StudiesUnited KingdomBlood GlucoseFolic AcidVitamin B 12FolateFolic acidGestational diabetes mellitusMicronutrientsPregnancyRisk factorsVitamin B12

Identifiers

PMID34296321
PMCPMC8423653
OpenAlexW3171215392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.