Evidence map›Paper›PMID 34296133›Full record

ArticleCerebral cortex communications2020

Lag Analysis of Fast fMRI Reveals Delayed Information Flow Between the Default Mode and Other Networks in Narcolepsy.

M Järvelä, V Raatikainen, A Kotila, J Kananen, V Korhonen, L Q Uddin, H Ansakorpi, V Kiviniemi

Open access · hybridAbstract read
In one paragraph

Article in Cerebral cortex communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Orexin effect on physiological pulsations of the human brain.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

M JärveläDepartment of Diagnostic Radiology, Medical Research Center (MRC), Oulu University Hospital, 90220 Oulu, Finland.ORCID 0000-0001-9899-3570
V RaatikainenDepartment of Diagnostic Radiology, Medical Research Center (MRC), Oulu University Hospital, 90220 Oulu, Finland.ORCID 0000-0001-9806-048X
A KotilaResearch Unit of Logopedics, University of Oulu, 90014 Oulu, Finland.ORCID 0000-0003-4631-9239
J KananenDepartment of Diagnostic Radiology, Medical Research Center (MRC), Oulu University Hospital, 90220 Oulu, Finland.ORCID 0000-0001-6831-8056
V KorhonenDepartment of Diagnostic Radiology, Medical Research Center (MRC), Oulu University Hospital, 90220 Oulu, Finland.ORCID 0000-0001-9403-4583
L Q UddinDepartment of Psychology, University of Miami, Coral Gables, 33124 FL, USA.ORCID 0000-0003-2278-8962
H AnsakorpiResearch Unit of Clinical Neuroscience, Neurology, University of Oulu, 90014 Oulu, Finland.ORCID 0000-0002-3685-7845
V KiviniemiDepartment of Diagnostic Radiology, Medical Research Center (MRC), Oulu University Hospital, 90220 Oulu, Finland.ORCID 0000-0003-0184-8524
Oulu University Hospital · FIUniversity of Miami · USUniversity of Oulu · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Narcolepsy is a chronic neurological disease characterized by dysfunction of the hypocretin system in brain causing disruption in the wake-promoting system. In addition to sleep attacks and cataplexy, patients with narcolepsy commonly report cognitive symptoms while objective deficits in sustained attention and executive function have been observed. Prior resting-state functional magnetic resonance imaging (fMRI) studies in narcolepsy have reported decreased inter/intranetwork connectivity regarding the default mode network (DMN). Recently developed fast fMRI data acquisition allows more precise detection of brain signal propagation with a novel dynamic lag analysis. In this study, we used fast fMRI data to analyze dynamics of inter resting-state network (RSN) information signaling between narcolepsy type 1 patients (NT1,

Indexed as

default mode networkfast fMRIinformation flowlag analysisnarcolepsy

Identifiers

PMID34296133
PMCPMC8153076
OpenAlexW3092487205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.