Evidence map›Paper›PMID 34296085›Full record

ArticleCerebral cortex communications2020

Near-Infrared Light Increases Functional Connectivity with a Non-thermal Mechanism.

Grzegorz M Dmochowski, Ahmed Duke Shereen, Destiny Berisha, Jacek P Dmochowski

2 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in Cerebral cortex communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05845216 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Effect of Transcranial Near InfraRed Light on Cerebral Function in Young and Healthy Older Subjects: a Functional Magnetic Resonance Imaging (fMRI) Study (TIROC)

TypeinterventionalSponsorUniversity Hospital, GrenobleRan2023 to 2026Enrolled64ConditionsHealthy VolunteersArmsACTIVE Transcranial photobiomodulation (tPBM), SHAM Transcranial photobiomodulation (tPBM)
NCT06352372 phase2completednot on this mapstarted 2024, after this paper: background citation

Safety and Efficacy of Transcranial Photobiomodulation (tPBM) for Individuals With Autism Spectrum Disorder and Epileptiform Activity

TypeinterventionalSponsorRichard FryeRan2024 to 2026Enrolled6ConditionsAutism Spectrum Disorder, EEG With Periodic Abnormalities, Epilepsy, Neurodevelopmental DisordersArmsnoninvasively delivered near infra-red (NIR) light - transcranial Photobiomodulation (tPBM)
3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.

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  7. Dose dependence and neurovascular mechanisms of the fMRI response to pulsed photobiomodulation in humans.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026
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  11. Transcranial photobiomodulation: an emerging therapeutic method to enhance brain bioenergetics.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Grzegorz M DmochowskiPrincess Margaret Cancer Centre, Toronto, ON M5G 1L7, Canada.
Ahmed Duke ShereenAdvanced Science Research Center, Graduate Center of the City University of New York, New York, NY 10031, USA.
Destiny BerishaDepartment of Biomedical Engineering, City College of New York, New York, NY 10031, USA.
Jacek P DmochowskiDepartment of Biomedical Engineering, City College of New York, New York, NY 10031, USA.
City College of New York · USPrincess Margaret Cancer Centre · CAThe Graduate Center, CUNY · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although techniques for noninvasive brain stimulation are under intense investigation, an approach that has received limited attention is transcranial photobiomodulation (tPBM), the delivery of near-infrared light to the brain with a laser or light-emitting diode directed at the scalp. Here we employed functional magnetic resonance imaging to measure the blood-oxygenation-level-dependent signal in

Indexed as

fMRIfunctional connectivitylow-level laser therapyneuromodulationphotobiomodulation

Identifiers

PMID34296085
PMCPMC8152883
OpenAlexW3011189435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.