ArticleFrontiers in molecular biosciences2021
Linear Peptides-A Combinatorial Innovation in the Venom of Some Modern Spiders.
Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 11 citations in OpenAlex.
- NMR Unveils Activity Mechanism of Linear Spider Venom Peptide Fragments Selected by Neural Networks Against Staphylococci Including MRSA.Pharmaceutics · 2025Article
- Computational exploration of global venoms for antimicrobial discovery with Venomics artificial intelligence.Nature communications · 2025Article
- Enlightening the toxinological dark matter of spider venom enzymes.npj biodiversity · 2024Article
- Article
- Molecular Diversity of Linear Peptides Revealed by Transcriptomic Analysis of the Venom Gland of the SpiderToxins · 2022Article
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Authors and funding
7 authors at 5 institutions in 4 countries.
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No grant is acknowledged in the PubMed record.
Abstract
In the venom of spiders, linear peptides (LPs), also called cytolytical or antimicrobial peptides, represent a largely neglected group of mostly membrane active substances that contribute in some spider species considerably to the killing power of spider venom. By next-generation sequencing venom gland transcriptome analysis, we investigated 48 spider species from 23 spider families and detected LPs in 20 species, belonging to five spider families (Ctenidae, Lycosidae, Oxyopidae, Pisauridae, and Zodariidae). The structural diversity is extraordinary high in some species: the lynx spider
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