Evidence map›Paper›PMID 34295894›Full record

ReviewFrontiers in cell and developmental biology2021

Cellular Heterogeneity of Mesenchymal Stem/Stromal Cells in the Bone Marrow.

Yo Mabuchi, Chikako Okawara, Simón Méndez-Ferrer, Chihiro Akazawa

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 56 citations in OpenAlex.

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  13. Human iPSC-Derived MSCs Induce Neurotrophic Effects and Improve Metabolic Activity in Acute Neuronal Injury Models.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Yo MabuchiWellcome-MRC Cambridge Stem Cell Institute, Department of Hematology, NHS Blood and Transplant, University of Cambridge, Cambridge, United Kingdom.
Chikako OkawaraDevelopment of Innovation in Fundamental and Scientific Nursing Care, Graduate School of Health Care Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Simón Méndez-FerrerWellcome-MRC Cambridge Stem Cell Institute, Department of Hematology, NHS Blood and Transplant, University of Cambridge, Cambridge, United Kingdom.
Chihiro AkazawaDepartment of Biochemistry and Biophysics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.
Tokyo Medical and Dental University · JPJuntendo University · JPUniversity of Cambridge · GB

Funding

Cancer Research UK 26670Medical Research Council MC_PC_17230Medical Research Council MR/V005421/1Wellcome Trust
6 · The paper itself

Abstract

Mesenchymal stem/stromal cells (MSCs) are present in various body tissues and help in maintaining homeostasis. The stemness of MSCs has been evaluated

Indexed as

cell surface markerheterogeneitymesenchymal stem cellsmyeloproliferative neoplasmsingle-cell analysisstem cell characterization

Identifiers

PMID34295894
PMCPMC8291416
OpenAlexW3179977914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.