Evidence map›Paper›PMID 34295880›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Alterations of Gut Microbiota in Patients With Intestinal Tuberculosis That Different From Crohn's Disease.

Cong He, Huan Wang, Chen Yu, Chao Peng, Xu Shu, Wangdi Liao, Zhenhua Zhu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. The gut microbiome: A line of defense against tuberculosis development.Frontiers in cellular and infection microbiology · 2023
    Review
  10. Role of adherent invasiveWorld journal of clinical cases · 2022
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Cong HeDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Huan WangDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Chen YuDepartment of Radiology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Chao PengDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Xu ShuDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Wangdi LiaoDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Zhenhua ZhuDepartment of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
First Affiliated Hospital of Nanchang University · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal tuberculosis (ITB) and Crohn's disease (CD) are chronic inflammatory bowel disorders that are associated with dysregulated mucosal immunity. The gut microbiota plays an important role in the regulation of host immunity and inflammatory response. Although mounting evidence has linked CD with the dysbiosis of gut microbiota, the characteristic profiles of mucosal bacteria in ITB remain unclear. The aim of this study was to assess the alterations of the gut microbiota in ITB and compare the microbial structure of ITB with CD. A total of 71 mucosal samples were collected from patients with ITB, CD, and healthy controls (HC), and then, 16S rRNA gene sequencing was performed. The overall composition of gut microbiota in ITB was strikingly different from HC, with the dominance of Proteobacteria and reduction of Firmicutes. Of note, the short-chain fatty acids (SCFAs)-producing bacteria such as

Indexed as

16S rRNA sequencingCrohn’s diseasegut microbiotaintestinal tuberculosisshort-chain fatty acids

Identifiers

PMID34295880
PMCPMC8290844
OpenAlexW3178096314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.