Evidence map›Paper›PMID 34295857›Full record

ArticleFrontiers in pediatrics2021

Case Report: Analysis of Inflammatory Cytokines IL-6, CCL2/MCP1, CCL5/RANTES, CXCL9/MIG, and CXCL10/IP10 in a Cystic Fibrosis Patient Cohort During the First Wave of the COVID-19 Pandemic.

Giulia Baresi, Mauro Giacomelli, Daniele Moratto, Marco Chiarini, Immacolata Claudia Conforti, Rita Padoan, Piercarlo Poli, Silviana Timpano, Francesca Caldarale, Raffaele Badolato

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Upregulation of inflammatory genes and pathways links obesity to severe COVID-19.Biochimica et biophysica acta. Molecular basis of disease · 2024
    Article
  5. Immune Response Dynamics and Biomarkers in COVID-19 Patients.International journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. IP-10 and complement activation as friend or foe in COVID-19.International journal of immunopathology and pharmacology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Giulia BaresiPediatrics Clinic, "Angelo Nocivelli" Institute of Molecular Medicine, Azienda Socio Sanitaria Territoriale Spedali Civili of Brescia, Brescia University, Brescia, Italy.
Mauro GiacomelliPediatrics Clinic, "Angelo Nocivelli" Institute of Molecular Medicine, Azienda Socio Sanitaria Territoriale Spedali Civili of Brescia, Brescia University, Brescia, Italy.
Daniele MorattoFlow Cytometry, Clinical Chemistry Laboratory, Azienda Socio Sanitaria Territoriale Spedali Civili of Brescia, Brescia, Italy.
Marco ChiariniFlow Cytometry, Clinical Chemistry Laboratory, Azienda Socio Sanitaria Territoriale Spedali Civili of Brescia, Brescia, Italy.
Immacolata Claudia ConfortiPediatrics Clinic, "Angelo Nocivelli" Institute of Molecular Medicine, Azienda Socio Sanitaria Territoriale Spedali Civili of Brescia, Brescia University, Brescia, Italy.
Rita PadoanPediatrics Clinic, "Angelo Nocivelli" Institute of Molecular Medicine, Azienda Socio Sanitaria Territoriale Spedali Civili of Brescia, Brescia University, Brescia, Italy.
Piercarlo PoliCystic Fibrosis Regional Support Center, Azienda Socio Sanitaria Territoriale Spedali Civili of Brescia, Brescia, Italy.
Silviana TimpanoCystic Fibrosis Regional Support Center, Azienda Socio Sanitaria Territoriale Spedali Civili of Brescia, Brescia, Italy.
Francesca CaldaralePediatrics Clinic, "Angelo Nocivelli" Institute of Molecular Medicine, Azienda Socio Sanitaria Territoriale Spedali Civili of Brescia, Brescia University, Brescia, Italy.
Raffaele BadolatoPediatrics Clinic, "Angelo Nocivelli" Institute of Molecular Medicine, Azienda Socio Sanitaria Territoriale Spedali Civili of Brescia, Brescia University, Brescia, Italy.
University of Brescia · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, data registered in the European countries revealed increasing cases of infection in cystic fibrosis (CF) patients. In the course of this pandemic, we enrolled 17 CF patients for a study evaluating inflammatory markers. One of them developed COVID

Indexed as

cystic fibrosiscytokinesinflammatory activationSARS-CoV-2 infectionT cell activation

Identifiers

PMID34295857
PMCPMC8291286
OpenAlexW3180718149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.