Evidence map›Paper›PMID 34295841›Full record

ReviewFrontiers in cellular and infection microbiology2021

Playing With Fire: Proinflammatory Virulence Mechanisms of Group A

Shyra Wilde, Anders F Johnson, Christopher N LaRock

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Virulence insights from ancient strep A.Communications biology · 2026
    Article
  5. Review
  6. From Infection to Autoimmunity:Microorganisms · 2025
    Review
  7. Article
  8. Article
  9. Characterization ofMicroorganisms · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Virulence factors ofFrontiers in microbiology · 2022
    Review
  19. Purinergic Signalling in Group AFrontiers in immunology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shyra WildeMicrobiology and Molecular Genetics Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.
Anders F JohnsonMicrobiology and Molecular Genetics Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.
Christopher N LaRockMicrobiology and Molecular Genetics Program, Graduate Division of Biological and Biomedical Sciences, Laney Graduate School, Emory University, Atlanta, GA, United States.
Emory University · US

Funding

Proteolytic regulation of the Streptococcus pyogenes cell surfaceR01AI153071 · NIAID · EMORY UNIVERSITY · PI LAROCK, CHRISTOPHER N · 2021 to 2025
$1.9M
NIAID NIH HHS R01 AI153071
6 · The paper itself

Abstract

Group A

Indexed as

Shock, SepticStreptococcal InfectionsHumansStreptococcus pyogenesVirulenceVirulence FactorsVirulence FactorsGroup A StreptococcusinflammationpathogenesisStreptococcus pyogenestoxinsvirulence factors

Identifiers

PMID34295841
PMCPMC8290871
OpenAlexW3177503355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.