Evidence map›Paper›PMID 34295840›Full record

Trial reportFrontiers in cellular and infection microbiology2021

Phenotypic and Genotypic Characterization of Novel Polyvalent Bacteriophages With Potent

Elliot Whittard, James Redfern, Guoqing Xia, Andrew Millard, Roobinidevi Ragupathy, Sladjana Malic, Mark C Enright

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Bacteriophage Therapy AgainstMicroorganisms · 2026
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Isolation andFrontiers in cellular and infection microbiology · 2023
    Article
  13. Article
  14. Antibiotics (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Elliot WhittardDepartment of Life Sciences, Manchester Metropolitan University, Manchester, United Kingdom.
James RedfernDepartment of Life Sciences, Manchester Metropolitan University, Manchester, United Kingdom.
Guoqing XiaLydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, United Kingdom.
Andrew MillardDepartment of Genetics and Genome Biology, University of Leicester, Leicester, United Kingdom.
Roobinidevi RagupathyDepartment of Life Sciences, Manchester Metropolitan University, Manchester, United Kingdom.
Sladjana MalicDepartment of Life Sciences, Manchester Metropolitan University, Manchester, United Kingdom.
Mark C EnrightDepartment of Life Sciences, Manchester Metropolitan University, Manchester, United Kingdom.
Manchester Metropolitan University · GBUniversity of Leicester · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phage therapy recently passed a key milestone with success of the first regulated clinical trial using systemic administration. In this single-arm non-comparative safety study, phages were administered intravenously to patients with invasive

Indexed as

BacteriophagesMethicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsGenotypeHumansStaphylococcusStaphylococcus aureusStaphylococcus Phagesbacteriophagebiofilmgenomicsmethicillin-resistant Staphylococcus aureusStaphylococcus aureus

Identifiers

PMID34295840
PMCPMC8290860
OpenAlexW3180642507

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.