Evidence map›Paper›PMID 34295838›Full record

ArticleFrontiers in cellular and infection microbiology2021

Pre-Diabetes Increases Tuberculosis Disease Severity, While High Body Fat Without Impaired Glucose Tolerance Is Protective.

Roma Sinha, Minh Dao Ngo, Stacey Bartlett, Helle Bielefeldt-Ohmann, Sahar Keshvari, Sumaira Z Hasnain, Meg L Donovan, Jessica C Kling, Antje Blumenthal, Chen Chen and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Article
  7. Review
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  11. The cause-effect relation of tuberculosis on incidence of diabetes mellitus.Frontiers in cellular and infection microbiology · 2023
    Review
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Roma SinhaTranslational Research Institute, Mater Research Institute, The University of Queensland, Brisbane, QLD, Australia.
Minh Dao NgoTranslational Research Institute, Mater Research Institute, The University of Queensland, Brisbane, QLD, Australia.
Stacey BartlettTranslational Research Institute, Mater Research Institute, The University of Queensland, Brisbane, QLD, Australia.
Helle Bielefeldt-OhmannSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Sahar KeshvariTranslational Research Institute, Mater Research Institute, The University of Queensland, Brisbane, QLD, Australia.
Sumaira Z HasnainTranslational Research Institute, Mater Research Institute, The University of Queensland, Brisbane, QLD, Australia.
Meg L DonovanThe University of Queensland Diamantina Institute, Brisbane, QLD, Australia.
Jessica C KlingThe University of Queensland Diamantina Institute, Brisbane, QLD, Australia.
Antje BlumenthalAustralian Infectious Diseases Research Centre - The University of Queensland, Brisbane, QLD, Australia.
Chen ChenSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD, Australia.
Kirsty R ShortSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia.
Katharina RonacherTranslational Research Institute, Mater Research Institute, The University of Queensland, Brisbane, QLD, Australia.
University of Queensland · AUTranslational Research Institute · AUMater Research · AU

Funding

Altered immune-endocrine axis in type 2 diabetes and tuberculosis riskR01AI116039 · NIAID · STELLENBOSCH UNIVERSITY · PI KLEYNHANS, LEANIE, RESTREPO, BLANCA I · 2015 to 2019
$1.7M
NIAID NIH HHS R01 AI116039
6 · The paper itself

Abstract

Type 2 diabetes (T2D) is a well-known risk factor for tuberculosis (TB), but little is known about pre-diabetes and the relative contribution of impaired glucose tolerance

Indexed as

Diabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Glucose IntolerancePrediabetic StateTuberculosisAdipose TissueAnimalsDiet, High-FatMiceMice, Inbred C57BLSeverity of Illness Indexdiabetesdisease severityhigh fat dietimpaired glucose toleranceinterferon responsesMycobacterium tuberculosispre-diabetestuberculosis

Identifiers

PMID34295838
PMCPMC8291147
OpenAlexW3180703110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.