Evidence map›Paper›PMID 34295824›Full record

ReviewFrontiers in oncology2021

Imaging-Genomics in Glioblastoma: Combining Molecular and Imaging Signatures.

Dongming Liu, Jiu Chen, Xinhua Hu, Kun Yang, Yong Liu, Guanjie Hu, Honglin Ge, Wenbin Zhang, Hongyi Liu

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dongming LiuDepartment of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Jiu ChenInstitute of Neuropsychiatry, The Affiliated Brain Hospital of Nanjing Medical University, Fourth Clinical College of Nanjing Medical University, Nanjing, China.
Xinhua HuDepartment of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Kun YangDepartment of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Yong LiuDepartment of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Guanjie HuDepartment of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Honglin GeDepartment of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Wenbin ZhangDepartment of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.
Hongyi LiuDepartment of Neurosurgery, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Based on artificial intelligence (AI), computer-assisted medical diagnosis can scientifically and efficiently deal with a large quantity of medical imaging data. AI technologies including deep learning have shown remarkable progress across medical image recognition and genome analysis. Imaging-genomics attempts to explore the associations between potential gene expression patterns and specific imaging phenotypes. These associations provide potential cellular pathophysiology information, allowing sampling of the lesion habitat with high spatial resolution. Glioblastoma (GB) poses spatial and temporal heterogeneous characteristics, challenging to current precise diagnosis and treatments for the disease. Imaging-genomics provides a powerful tool for non-invasive global assessment of GB and its response to treatment. Imaging-genomics also has the potential to advance our understanding of underlying cancer biology, gene alterations, and corresponding biological processes. This article reviews the recent progress in the utilization of the imaging-genomics analysis in GB patients, focusing on its implications and prospects in individualized diagnosis and management.

Indexed as

artificial intelligencedeep learningglioblastomaimaging genomicsmachine learningradiomics

Identifiers

PMID34295824
PMCPMC8290166

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.