Evidence map›Paper›PMID 34295318›Full record

ArticleFrontiers in microbiology2021

Dysbiosis of Gut Microbiota in Patients With Acute Myocardial Infarction.

Ying Han, Zhaowei Gong, Guizhi Sun, Jing Xu, Changlu Qi, Weiju Sun, Huijie Jiang, Peigang Cao, Hong Ju

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 2 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 2 syntheses or guidelines pooled it, 110 citations in OpenAlex.

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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Ying HanDepartment of Cardiovascular, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Zhaowei GongDepartment of Cardiovascular, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Guizhi SunDepartment of Cardiovascular, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Jing XuDepartment of Cardiovascular, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China.
Changlu QiCollege of Bioinformatics Science and Technology, Harbin Medical University, Harbin, China.
Weiju SunDepartment of Cardiovascular, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Huijie JiangDepartment of Radiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Peigang CaoDepartment of Cardiology, Heilongjiang Province Land Reclamation Headquarters General Hospital, Harbin, China.
Hong JuDepartment of Information Engineering, Heilongjiang Biological Science and Technology Career Academy, Harbin, China.
Harbin Medical University · CNFourth Affiliated Hospital of Harbin Medical University · CNHeilongjiang Academy of Forestry · CNHeilongjiang Academy of Land Reclamation Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute myocardial infarction (AMI) continues as the main cause of morbidity and mortality worldwide. Interestingly, emerging evidence highlights the role of gut microbiota in regulating the pathogenesis of coronary heart disease, but few studies have systematically assessed the alterations and influence of gut microbiota in AMI patients. As one approach to address this deficiency, in this study the composition of fecal microflora was determined from Chinese AMI patients and links between gut microflora and clinical features and functional pathways of AMI were assessed. Fecal samples from 30 AMI patients and 30 healthy controls were collected to identify the gut microbiota composition and the alterations using bacterial 16S rRNA gene sequencing. We found that gut microflora in AMI patients contained a lower abundance of the phylum

Indexed as

16S rRNA geneacute myocardial infarctiondysbiosisgut microflorapatients

Identifiers

PMID34295318
PMCPMC8290895
OpenAlexW3179042435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.