ReviewJournal of pain research2021
The American Society of Pain and Neuroscience (ASPN) Best Practices and Guidelines for the Interventional Management of Cancer-Associated Pain.
Review in Journal of pain research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 3 syntheses or guidelines pooled it, 97 citations in OpenAlex.
- Barriers to interventional pain management in patients with cancer: a systematic review.BMC palliative care · 2026Pooled it
- Management of patients with cancer pain: an evaluation of AGREE II-based clinical practice guidelines.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Intrathecal Drug Delivery Systems for Cancer Pain: A Health Technology Assessment.Ontario health technology assessment series · 2024Pooled it
- Radiofrequency Ablation for the Treatment of Bone Metastases: Results of the SPARTA Study.Cardiovascular and interventional radiology · 2026Trial
- Molecular and Cellular Mechanisms of Spinal Cord Stimulation: Linking Dorsal Horn Circuits, Glia, and ECAP-Guided Therapy.International journal of molecular sciences · 2026Review
- Perioperative considerations for patients with multiple myeloma.European journal of anaesthesiology and intensive care · 2026Review
- Spinal cord stimulation for atypical anterior chest wall complex regional pain syndrome: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Management of acute cancer-related pain in a patient with opioid use disorder: a case report.Journal of medical case reports · 2026Article
- Implementing measurement-based care in the analgesic management of cancer pain patients receiving intrathecal drug infusion.Scientific reports · 2026Observational
- Radiopharmaceuticals for the Treatment of Chronic Cancer Pain.Current pain and headache reports · 2026Review
- Pulsed radiofrequency of S2-4 nerve roots vs ganglion impar neurolysis for severe perineal cancer pain.Pain reports · 2026Article
- Troubleshooting intrathecal pumps in pain management: A clinical review.Interventional pain medicine · 2026Review
- Genotoxicity effects in Cancer Patients: Evaluation by Micronucleus and Comet Assays and Correlation with Biochemical and Hematological Indices.F1000Research · 2026Article
- Sunlight PDT leveraging NIR-II nanospray: painless, hemostatic, anti-inflammatory therapy towards diabetic wound infections.National science review · 2026Article
- Retrograde Intrathecal Catheter Placement at L5/S1 for Sacropelvic Cancer Pain: A Pilot Feasibility Study.Journal of pain research · 2026Article
- Intrathecal Drug Delivery Systems for Chronic Pain Management: A Narrative Review of Pharmacologic Agents, Clinical Applications, and Considerations.Pharmacy (Basel, Switzerland) · 2025Review
- Chronic Pain in the Cancer Survivor.Current pain and headache reports · 2025Review
- Assessing the availability, readability, and content of online patient Education materials for cancer pain interventions: A cross-sectional analysis of major cancer center websites.Interventional pain medicine · 2025Article
- The Missing Link: Integrating Interventional Pain Management in the Era of Multimodal Oncology.Pain and therapy · 2025Review
- A Review on the Management of Symptoms in Patients with Incurable Cancer.Current oncology (Toronto, Ont.) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 20 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Moderate to severe pain occurs in many cancer patients during their clinical course and may stem from the primary pathology, metastasis, or as treatment side effects. Uncontrolled pain using conservative medical therapy can often lead to patient distress, loss of productivity, shorter life expectancy, longer hospital stays, and increase in healthcare utilization. Various publications shed light on strategies for conservative medical management for cancer pain and a few international publications have reviewed limited interventional data. Our multi-institutional working group was assembled to review and highlight the body of evidence that exists for opioid utilization for cancer pain, adjunct medication such as ketamine and methadone and interventional therapies. We discuss neurolysis via injections, neuromodulation including targeted drug delivery and spinal cord stimulation, vertebral tumor ablation and augmentation, radiotherapy and surgical techniques. In the United States, there is a significant variance in the interventional treatment of cancer pain based on fellowship training. As a first of its kind, this best practices and interventional guideline will offer evidenced-based recommendations for reducing pain and suffering associated with malignancy.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.