Evidence map›Paper›PMID 34294939›Full record

ReviewPathologica2021

The histomorphological and molecular landscape of colorectal adenomas and serrated lesions.

Francesca Galuppini, Matteo Fassan, Luca Mastracci, Roberta Gafà, Marcello Lo Mele, Stefano Lazzi, Andrea Remo, Paola Parente, Alessandro D'Amuri, Claudia Mescoli and 2 more

Abstract readReview
In one paragraph

Review in Pathologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Francesca GaluppiniSurgical Pathology Unit, Department of Medicine (DIMED), University of Padua, Italy.
Matteo FassanSurgical Pathology Unit, Department of Medicine (DIMED), University of Padua, Italy.
Luca MastracciAnatomic Pathology, Ospedale Policlinico San Martino IRCCS, Genova, Italy.
Roberta GafàDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.
Marcello Lo MeleSurgical Pathology Unit, Department of Medicine (DIMED), University of Padua, Italy.
Stefano LazziDepartment of Medical Biotechnology, University of Siena, Siena, Italy.
Andrea RemoPathology Unit, Service Department, ULSS9 "Scaligera", Verona, Italy.
Paola ParentePathology Unit, Fondazione IRCCS Ospedale Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.
Alessandro D'AmuriAnatomic Pathology Unit, "A. Perrino" Hospital, Brindisi, Italy.
Claudia MescoliSurgical Pathology Unit, Department of Medicine (DIMED), University of Padua, Italy.
Fabiana TatangeloDepartment of Pathology, Istituto Nazionale Tumori, IRCCS-Fondazione "G. Pascale", Naples, Italy.
Giovanni LanzaDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2019 WHO classification of digestive system tumors significantly reformed the classificatory definition of serrated lesions of the colorectal mucosa and added new essential diagnostic criteria for both conventional adenomas and hereditary gastrointestinal polyposis syndromes. Histopathological examination of colorectal adenocarcinoma precursors lesions represents an important segment of daily clinical practice in a pathology department and is essential for the implementation of current colorectal adenocarcinoma secondary prevention strategies. This overview will focus on a schematic histopathological and molecular classification of precursor lesions arising within colorectal mucosa.

Indexed as

AdenocarcinomaAdenomaColonic PolypsColorectal NeoplasmsHumansMutationcolorectal adenomasdysplasiaserrated lesions

Identifiers

PMID34294939
PMCPMC8299322

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.