Evidence map›Paper›PMID 34294868›Full record

ArticlePediatric research2022

Higher CPAP levels improve functional residual capacity at birth in preterm rabbits.

Tessa Martherus, Michelle K Croughan, Kelly J Crossley, Megan J Wallace, Erin V McGillick, Marta Thio, Charles C Roehr, James T Pearson, Katie Lee, Gary Ruben and 3 more

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Pediatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Observational
  2. OcclusiveEuropean respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Tessa MartherusWillem-Alexander Children's Hospital, department of Pediatrics, division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands. t.martherus@lumc.nl.
Michelle K CroughanSchool of Physics and Astronomy, Monash University, Melbourne, VIC, Australia.
Kelly J CrossleyThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
Megan J WallaceThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
Erin V McGillickThe Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
Marta ThioNewborn Research Centre, The Royal Women's Hospital, Melbourne, VIC, Australia.
Charles C RoehrDepartment of Paediatrics and Neonatology, Oxford University, Oxford, UK.
James T PearsonMonash Biomedical Imaging, Monash University, Clayton, VIC, Australia.
Katie LeeSchool of Physics and Astronomy, Monash University, Melbourne, VIC, Australia.
Gary RubenSchool of Physics and Astronomy, Monash University, Melbourne, VIC, Australia.
Marcus J KitchenSchool of Physics and Astronomy, Monash University, Melbourne, VIC, Australia.
Arjan B Te Pas *Willem-Alexander Children's Hospital, department of Pediatrics, division of Neonatology, Leiden University Medical Center, Leiden, The Netherlands.
Stuart B Hooper *The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, VIC, Australia.
Hudson Institute of Medical Research · AUMonash University · AULeiden University Medical Center · NLNational Cerebral and Cardiovascular Center · JPRoyal Women's Hospital · AUUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPreterm infants are commonly supported with 4-8 cm H

methodsPreterm rabbits delivered at 29/32 days (~26-28 weeks human) gestation received 0, 5, 8, 12, 15 cm H

resultsFRC was lower in the 0 (6.8 (1.0-11.2) mL/kg) and 5 (10.1 (1.1-16.8) mL/kg) compared to the 15 (18.8 (10.9-22.4) mL/kg) cm H

conclusionIn all, 15 cm H IMPACT: Although preterm infants are commonly supported with 4-8 cm H

Indexed as

ApneaPneumothoraxAnimalsContinuous Positive Airway PressureFunctional Residual CapacityHumansInfant, NewbornInfant, PrematureRabbits

Identifiers

PMID34294868
OpenAlexW3184473363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.