ArticleScientific reports2021
Pulsation of anastomotic vortex veins in pachychoroid spectrum diseases.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Article
- Association of Vortex Vein Morphology with Punctate Hyperfluorescence on ICGA in Neovascular Age-Related Macular Degeneration.Journal of clinical medicine · 2026Article
- Association between Choroidal Vascular Hyperpermeability and Vortex Vein Anastomoses in Central Serous Chorioretinopathy.Ophthalmology science · 2026Article
- Reduction in choroidal thickness associated with the progression of pachychoroid spectrum diseases.Japanese journal of ophthalmology · 2025Article
- Treatment of central serous chorioretinopathy: new options for an old disease.Eye (London, England) · 2025Review
- Article
- Structural changes in vortex vein ampullae in eyes with pachychoroid-spectrum disorder.Scientific reports · 2025Article
- Association between the arm-to-choroidal circulation time and clinical profile in patients with polypoidal choroidal vasculopathy.Japanese journal of ophthalmology · 2024Article
- Relationship between pulsation of posterior vortex vein, choroidal thickness, and choroidal vascular hyperpermeability in polypoidal choroidal vasculopathy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Attenuation of irradiated choroid and its regional vortex veins in central serous chorioretinopathy after photodynamic therapy.Scientific reports · 2023Article
- Intervortex Venous Anastomosis in the Macula in Central Serous Chorioretinopathy Imaged by En Face Optical Coherence Tomography.Journal of clinical medicine · 2023Article
- Quadrant laser photocoagulation trial to ameliorate choroidal congestion in central serous chorioretinopathy.Japanese journal of ophthalmology · 2023Article
- Choroidal arteriovenous anastomoses: a hypothesis for the pathogenesis of central serous chorioretinopathy and other pachychoroid disease spectrum abnormalities.Acta ophthalmologica · 2022Article
- Angiopoietin-1 Is Required for Vortex Vein and Choriocapillaris Development in Mice.Arteriosclerosis, thrombosis, and vascular biology · 2022Article
- A new insight into pachychoroid diseases: Remodeling of choroidal vasculature.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Review
- Clinical characteristics and pachychoroid incidence in Japanese patients with neovascular age-related macular degeneration.Scientific reports · 2022Article
- Article
- Inversion of Asymmetric Vortex Vein Dilatation in Pachychoroid Spectrum Diseases.Ophthalmology scienceArticle
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accumulating evidence points to pachychoroid possibly being caused by vortex vein congestion which results in remodeling of choroidal drainage routes via intervortex vein anastomosis. This hypothesis prompted us to investigate vortex vein hemodynamics by studying videos of indocyanine green angiography (ICGA) in a retrospective case series of 295 eyes with pachychoroid spectrum diseases. In the early phase of the video-ICGA, pulsatile vortex venous flow was observed in 76 eyes (25.8%) at the vortex veins connected with anastomosis between superior and inferior vortex veins. The patients with pulsatile vortex venous flow were significantly older than those without pulsatile vortex venous flow (67.8 ± 13.2 vs. 63.9 ± 14.5 years, P < 0.05). Pulsatile vortex venous flow was 1.84 times more common in the inferior quadrants than in the superior quadrants. Interestingly, 14 of 76 eyes (18.4%) with pulsatile vortex venous flow showed retrograde pulsatile blood flow in the vortex veins. This retrograde pulsatile blood flow was 2.50 times more common in the inferior than in the superior quadrants. These findings indicate altered vortex vein hemodynamics due to vortex vein congestion in pachychoroid spectrum diseases.
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