Evidence map›Paper›PMID 34294132›Full record

ReviewParasites & vectors2021

Abdominal angiostrongyliasis in the Americas: fifty years since the discovery of a new metastrongylid species, Angiostrongylus costaricensis.

Alicia Rojas, Arnaldo Maldonado-Junior, Javier Mora, Alessandra Morassutti, Rubens Rodriguez, Alberto Solano-Barquero, Anamariela Tijerino, Marianela Vargas, Carlos Graeff-Teixeira

Open access · goldAbstract readPortraitReview
In one paragraph

Review in Parasites & vectors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 35 citations in OpenAlex.

  1. Immunodominant IgM Epitopes of theInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Insights into the genetic diversity ofFood and waterborne parasitology · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Identification of Novel Genes and Proteoforms inPathogens (Basel, Switzerland) · 2022
    Article
  11. Membranes · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Alicia RojasLaboratory of Helminthology, Centro de Investigación en Enfermedades Tropicales, University of Costa Rica, San José, Costa Rica. anaalicia.rojas@ucr.ac.cr.ORCID http://orcid.org/0000-0003-2007-7198
Arnaldo Maldonado-JuniorLaboratório de Biologia e Parasitologia de Mamíferos Silvestres Reservatórios, Fundação Oswaldo Cruz - FIOCRUZ, Rio de Janeiro, RJ, Brazil.
Javier MoraLaboratory of Helminthology, Centro de Investigación en Enfermedades Tropicales, University of Costa Rica, San José, Costa Rica.
Alessandra MorassuttiInstituto de Patologia e Biologia Molecular de Passo Fundo, School of Medicine, IMED Passo Fundo, Rio Grande do Sul, Brazil.
Rubens RodriguezInstituto de Patologia e Biologia Molecular de Passo Fundo, School of Medicine, IMED Passo Fundo, Rio Grande do Sul, Brazil.
Alberto Solano-BarqueroLaboratory of Helminthology, Centro de Investigación en Enfermedades Tropicales, University of Costa Rica, San José, Costa Rica.
Anamariela TijerinoNational Reference Center of Parasitology, Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud, Cartago, Costa Rica.
Marianela VargasNational Reference Center of Parasitology, Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud, Cartago, Costa Rica.
Carlos Graeff-TeixeiraNucleo de Doenças Infecciosas, Centro de Ciências da Saúde, Universidade Federal do Espírito Santo, Vitória, Brazil.
Universidad de Costa Rica · CRAtitus Educação · BRInstituto Costarricense de Investigación y Enseñanza en Nutrición y Salud · CRFundação Oswaldo Cruz · BRUniversidade Federal do Espírito Santo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angiostrongylus costaricensis is a zoonotic parasitic nematode described for the first time in 1971 by Pedro Morera and Rodolfo Céspedes in Costa Rica. This parasite causes an infection known as abdominal angiostrongyliasis, affecting mainly school-aged children and young adults. Infection with A. costaricensis has been associated with a myriad of rodent and mollusk species in the Americas and the Caribbean, as its natural hosts and reservoirs. In this commemorative review, we highlight the extensive research collected through a 50-year journey, which includes ecological, pathological, and molecular studies on A. costaricensis and its implicated disease. We also identify major knowledge gaps in its evolutionary history, the ecological role of imported and invasive mollusk species, and immune response. We propose that the advent of -omics analyses will allow us to gather novel information regarding A. costaricensis biology and infection dynamics, as well as to promote the design of much-needed sensitive and specific diagnostic tools.

Indexed as

AmericasAngiostrongylusAnimalsCaribbean RegionDisease ReservoirsHost SpecificityHumansImmunityIntroduced SpeciesLarvaLife Cycle StagesMolluscaRodentiaStrongylida InfectionsZoonosesAbdominal angiostrongyliasisAngiostrongylus costaricensisEosinophilic enteritisHelminthiasisZoonosis

Identifiers

PMID34294132
PMCPMC8296644
OpenAlexW3184332680

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.