Evidence map›Paper›PMID 34293534›Full record

ArticleParkinsonism & related disorders2021

A French survey on the lockdown consequences of COVID-19 pandemic in Parkinson's disease. The ERCOPARK study.

Margherita Fabbri, Clémence Leung, Guillaume Baille, Matthieu Béreau, Christine Brefel Courbon, Giovanni Castelnovo, Nicolas Carriere, Philippe Damier, Luc Defebvre, Anne Doe de Maindreville and 10 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Parkinsonism & related disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04466839 (Evaluation of the Containment Impact Linked to the Covid-19 Pandemic in a Population of Parkinson Patients), which is not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04466839 completednot on this map

Evaluation of the Containment Impact Linked to the Covid-19 Pandemic in a Population of Parkinson Patients

TypeobservationalSponsorUniversity Hospital, ToulouseRan2020 to 2020Enrolled411ConditionsParkinson Disease, COVIDArmsQuestionnaire and interview
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
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  4. Article
  5. Article
  6. Observational
  7. Movement Disorders and SARS-CoV-2.Movement disorders clinical practice · 2023
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  17. Spotlight on non-motor symptoms and Covid-19.International review of neurobiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 12 institutions in 1 country.

Margherita FabbriService de Neurologie, Centre Hospitalier Universitaire, Toulouse, France; France CHU de Toulouse, Université de Toulouse-Toulouse 3, INSERM, UMR1214 Toulouse NeuroImaging Centre "TONIC," Center of Excellence in Neurodegeneration (CoEN), NeuroToul, Centre Expert Parkinson de Toulouse, Centre d'Investigation Clinique CIC1436, NS-Park/FCRIN Network, Services de Neurologie et de Pharmacologie Clinique, UMR 1048 Institute for Cardiovascular Diseases, Toulouse, France. Electronic address: margheritafabbrimd@gmail.com.
Clémence LeungService de Neurologie, Centre Hospitalier Universitaire, Toulouse, France.
Guillaume BailleService de Neurologie, Hôpital Delafontaine, Saint-Denis, France.
Matthieu BéreauService de Neurologie, Centre Hospitalier Universitaire, Besançon, France.
Christine Brefel CourbonService de Neurologie, Centre Hospitalier Universitaire, Toulouse, France; France CHU de Toulouse, Université de Toulouse-Toulouse 3, INSERM, UMR1214 Toulouse NeuroImaging Centre "TONIC," Center of Excellence in Neurodegeneration (CoEN), NeuroToul, Centre Expert Parkinson de Toulouse, Centre d'Investigation Clinique CIC1436, NS-Park/FCRIN Network, Services de Neurologie et de Pharmacologie Clinique, UMR 1048 Institute for Cardiovascular Diseases, Toulouse, France; Service de Pharmacologie Médicale et Clinique - CHU Toulouse Université de Toulouse, France.
Giovanni CastelnovoService de Neurologie, Centre Hospitalier Universitaire, NS-Park/FCRIN Network, Nîmes, France.
Nicolas CarriereService de Neurologie, Centre Hospitalier Universitaire, NS-Park/FCRIN Network, Lille, France.
Philippe DamierService de Neurologie, Centre Hospitalier Universitaire, NS-Park/FCRIN Network, Nantes, France.
Luc DefebvreService de Neurologie, Centre Hospitalier Universitaire, NS-Park/FCRIN Network, Lille, France.
Anne Doe de MaindrevilleService de Neurologie, Centre Hospitalier Universitaire, NS-Park/FCRIN Network, Reims, France.
Frederique FluchereService de Neurologie, Centre Hospitalier Universitaire la Timone, Aix-Marseille University, NS-Park/FCRIN Network, France.
Marie FuzzattiAssociation France Parkinson, France.
David GrabliService de Neurologie, Centre Hospitalier Universitaire, NS-Park/FCRIN Network, Pitié-Salpêtrière, France.
David MalteteService de Neurologie, Centre Hospitalier Universitaire, Rouen, France; INSERM U1239, Laboratoire de Différenciation et Communication Neuronale et Neuroendocrinienne, NS-Park/FCRIN Network, Mont-Saint-Aignan, France.
Vanessa RousseauService de Pharmacologie Médicale et Clinique - CHU Toulouse Université de Toulouse, France; Unité MeDatAS, Centre d'Investigation Clinique, Centre Hospitalier Universitaire, Toulouse, France.
Agnès Sommet AService de Pharmacologie Médicale et Clinique - CHU Toulouse Université de Toulouse, France; Unité MeDatAS, Centre d'Investigation Clinique, Centre Hospitalier Universitaire, Toulouse, France.
Claire ThalamasFrance CHU de Toulouse, Université de Toulouse-Toulouse 3, INSERM, UMR1214 Toulouse NeuroImaging Centre "TONIC," Center of Excellence in Neurodegeneration (CoEN), NeuroToul, Centre Expert Parkinson de Toulouse, Centre d'Investigation Clinique CIC1436, NS-Park/FCRIN Network, Services de Neurologie et de Pharmacologie Clinique, UMR 1048 Institute for Cardiovascular Diseases, Toulouse, France.
Claire ThiriezService de Neurologie, Centre Hospitalier Universitaire, NS-Park/FCRIN Network, Caen, France.
Olivier RascolService de Neurologie, Centre Hospitalier Universitaire, Toulouse, France; France CHU de Toulouse, Université de Toulouse-Toulouse 3, INSERM, UMR1214 Toulouse NeuroImaging Centre "TONIC," Center of Excellence in Neurodegeneration (CoEN), NeuroToul, Centre Expert Parkinson de Toulouse, Centre d'Investigation Clinique CIC1436, NS-Park/FCRIN Network, Services de Neurologie et de Pharmacologie Clinique, UMR 1048 Institute for Cardiovascular Diseases, Toulouse, France; Service de Pharmacologie Médicale et Clinique - CHU Toulouse Université de Toulouse, France.
Fabienne Ory-MagneService de Neurologie, Centre Hospitalier Universitaire, Toulouse, France; France CHU de Toulouse, Université de Toulouse-Toulouse 3, INSERM, UMR1214 Toulouse NeuroImaging Centre "TONIC," Center of Excellence in Neurodegeneration (CoEN), NeuroToul, Centre Expert Parkinson de Toulouse, Centre d'Investigation Clinique CIC1436, NS-Park/FCRIN Network, Services de Neurologie et de Pharmacologie Clinique, UMR 1048 Institute for Cardiovascular Diseases, Toulouse, France.
Inserm · FRCentre Hospitalier Universitaire de Toulouse · FRCentre Hospitalier Universitaire de Lille · FRAix-Marseille Université · FRCentre Hospitalier Saint-Denis · FRCentre Hospitalier Universitaire de Besançon · FRCentre Hospitalier Universitaire de Caen Normandie · FRCentre Hospitalier Universitaire de Nantes · FRCentre Hospitalier Universitaire de Nîmes · FRCentre Hospitalier Universitaire de Reims · FRFrance Parkinson · FRSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2020 the coronavirus disease 19 (COVID-19) pandemic imposed a total and sudden lockdown. We aimed to investigate the consequences of the first COVID-19 lockdown (mid-March - mid-April 2020) on motor and non-motor symptoms (NMS) in a cohort of French people with Parkinson's disease (PwP).

methodsPwP were enrolled either by an on-line survey sent from the national France Parkinson association (FP) to reach the French community of PwP or as part of outpatients' telemedicine visits followed by an hospital-based Parkinson Expert Center (PEC). All patients were evaluated using the same standardized questionnaire assessing motor and NMS (including a list of most disabling, new or worsened symptoms and Patient's Global Impression-Improvement scales [PGI-I]) psycho-social queries and quality of life.

results2653 PwP were included: 441 (16.6%) in the PEC group and 2122 (83.4%) in the community-based group. Physiotherapy was interrupted among 88.6% of the patients. 40.9% referred a clinical modification of their symptoms. Based on the questionnaire, pain (9.3%), rigidity (9.1%) and tremor (8.5%) were the three most frequently new or worsened reported symptoms. Based on the PGI-I, the motor symptoms were the most affected domain, followed by pain and psychic state. PwP in community-based group tended to have more frequent worsening for motor symptoms, motor complications, pain and confusion than those of the PEC group.

conclusionsThe first COVID-19 lockdown had a negative impact on motor and NMS of PwP. Efforts should be allocated to avoid interruption of care, including physiotherapy and physical activities and implement telemedicine. .

Indexed as

COVID-19PandemicsCohort StudiesCommunicable Disease ControlFranceHumansMuscle RigidityPainParkinson DiseasePhysical Therapy ModalitiesQuality of LifeQuarantineRemote ConsultationSurveys and QuestionnairesTelemedicineTremorMotor symptomsNon-motor symptomsPandemicParkinson's diseaseSARS-CoV-2 lock down

Identifiers

PMID34293534
PMCPMC9272278
OpenAlexW3181611616

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.