Evidence map›Paper›PMID 34293368›Full record

ArticleThe Journal of pediatrics2021

Stable Rates of Low Vitamin D Status Among Children Despite Increased Testing: A Population-Based Study.

Alyssa A Kerber, Mitchell M Pitlick, Anna E Kellund, Amy L Weaver, Seema Kumar, Avni Y Joshi

Open access · greenAbstract read
In one paragraph

Article in The Journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alyssa A KerberDepartment of Pediatric and Adolescent Medicine, Children's Center, Mayo Clinic, Rochester, MN.
Mitchell M PitlickDivision of Allergic Disease, Department of Medicine, Mayo Clinic, Rochester, MN.
Anna E KellundDepartment of Pediatric and Adolescent Medicine, Children's Center, Mayo Clinic, Rochester, MN.
Amy L WeaverDivision of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN.
Seema KumarDivision of Pediatric Endocrinology, Children's Center, Mayo Clinic, Rochester, MN.
Avni Y JoshiDivision of Allergic Disease, Department of Medicine, Mayo Clinic, Rochester, MN; Division of Pediatric Allergy and Immunology, Children's Center, Mayo Clinic, Rochester, MN. Electronic address: Joshi.avni@mayo.edu.
Children's Center · USMayo Clinic · USWinnMed · US

Funding

Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR33AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2020 to 2022
$2.4M
Interdisciplinary Infrastructure for Aging Research: Rochester Epidemiology ProjectR21AG058738 · NIA · MAYO CLINIC ROCHESTER · PI LEBRASSEUR, NATHAN K, OLSON, JANET E · 2018 to 2019
$437k
NIA NIH HHS R21 AG058738NIA NIH HHS R33 AG058738
6 · The paper itself

Abstract

objectiveTo determine the trends in testing and incidence of vitamin D deficiency/insufficiency in Olmsted County, Minnesota over a 16-year period. STUDY

designThe Rochester Epidemiology Project (REP) was used to identify Olmsted County, Minnesota residents aged <19 years who had 25-hydroxyvitamin D [25(OH)D] levels measured between January 2, 2002 and December 31, 2017. Using each patient's first 25(OH)D measurement during this period, patients were categorized into 3 groups: <20 ng/mL, 20-50 ng/mL, and >50 ng/mL. Vitamin D deficiency/insufficiency was defined as a total 25(OH)D level of <20 ng/mL.

resultsThere was a 42-fold increase in the proportion of the county's pediatric population tested each year, starting at 3.7 per 10 000 persons in 2002 and increasing to 156.1 per 10 000 persons in 2017. The largest increase in testing occurred in children aged ≥10 years, specifically the females in this age group, in whom we observed a 90-fold increase from 2002 to 2017. During the 16-year period, the incidence of vitamin D deficiency/insufficiency (per 10 000 persons) increased from 1.7 in 2002-2003 to 19.9 in 2016-2017, but the proportion that were tested and had vitamin D deficiency/insufficiency remained stable, with rates of 21.9% (95% CI, 16.1%-29.1%) in 2006-2007 and 18.5% (95% CI, 16.0%-21.2%) in 2016-2017.

conclusionsThe proportion of the county's pediatric population who underwent vitamin D testing increased from 2002 to 2017, in parallel to the increased incidence of vitamin D deficiency/insufficiency, but the proportion tested that had vitamin D deficiency/insufficiency remained stable over time.

Indexed as

AdolescentBiomarkersChildChild, PreschoolFemaleHumansIncidenceInfantInfant, NewbornMaleMinnesotaPractice Patterns, Physicians'Retrospective StudiesRisk FactorsVitamin DVitamin D Deficiency25-hydroxyvitamin DBiomarkersVitamin Ddeficiencyincidencepopulationtrendsvitamin D

Identifiers

PMID34293368
PMCPMC9156447
OpenAlexW3185044833

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.