ArticleCell reports2021
Behavior determines the hippocampal spatial mapping of a multisensory environment.
Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Olfactory spatial memory: a systematic review and meta-analysis.Scientific reports · 2025Pooled it
- Dual computational systems in the development and evolution of mammalian brains.Science advances · 2026Article
- Multisensory coding of audiovisual movies in the human hippocampus.bioRxiv : the preprint server for biology · 2026Article
- Adaptation of hippocampal spatial and contextual representations to task structure.Science advances · 2025Article
- Distinct brain regions map olfactory and visual spaces.bioRxiv : the preprint server for biology · 2025Article
- Article
- A flexible hippocampal population code for experience relative to reward.Nature neuroscience · 2025Article
- Article
- Navigating uncertainty: reward location variability induces reorganization of hippocampal spatial representations.bioRxiv : the preprint server for biology · 2025Article
- Representational similarity analysis reveals cue-independent spatial representations for landmarks and self-motion cues in human retrosplenial cortex.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- The medial entorhinal cortex encodes multisensory spatial information.Cell reports · 2024Article
- Aberrant hippocampal CaeLife · 2024Article
- Multiphoton imaging of hippocampal neural circuits: techniques and biological insights into region-, cell-type-, and pathway-specific functions.Neurophotonics · 2024Review
- Hippocampal-dependent navigation in head-fixed mice using a floating real-world environment.Scientific reports · 2024Article
- Article
- Hippocampal sequences span experience relative to rewards.bioRxiv : the preprint server for biology · 2024Article
- Aberrant hippocampal CabioRxiv : the preprint server for biology · 2024Article
- Odors in space.Frontiers in neural circuits · 2024Review
- Adult-born granule cells facilitate remapping of spatial and non-spatial representations in the dentate gyrus.Neuron · 2023Article
- Full field-of-view virtual reality goggles for mice.Neuron · 2023Article
Corrections and comments
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4 authors.
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Abstract
Animals behave in multisensory environments guided by various modalities of spatial information. Mammalian navigation engages a cognitive map of space in the hippocampus. Yet it is unknown whether and how this map incorporates multiple modalities of spatial information. Here, we establish two behavioral tasks in which mice navigate the same multisensory virtual environment by either pursuing a visual landmark or tracking an odor gradient. These tasks engage different proportions of visuo-spatial and olfacto-spatial mapping CA1 neurons and different population-level representations of each sensory-spatial coordinate. Switching between tasks results in global remapping. In a third task, mice pursue a target of varying sensory modality, and this engages modality-invariant neurons mapping the abstract behaviorally relevant coordinate irrespective of its physical modality. These findings demonstrate that the hippocampus does not necessarily map space as one coherent physical variable but as a combination of sensory and abstract reference frames determined by the subject's behavioral goal.
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