Evidence map›Paper›PMID 34292752›Full record

ArticleOrganic letters2021

Synthesis of Aristoquinoline Enantiomers and Their Evaluation at the α3β4 Nicotinic Acetylcholine Receptor.

Malaika D Argade, Carolyn J Straub, Lisa E Rusali, Bernard D Santarsiero, Andrew P Riley

Abstract read
In one paragraph

Article in Organic letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. 9-Hydroxyaristoquinolone: A New Indole Alkaloid Isolated fromInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Review
  8. Syntheses ofSynlett : accounts and rapid communications in synthetic organic chemistry · 2022
    Article
  9. Synthesis of (-)-halichonic acid and (-)-halichonic acid B.Beilstein journal of organic chemistry · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Malaika D ArgadeDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Carolyn J StraubDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-8976-5039
Lisa E RusaliDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.
Bernard D SantarsieroDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-9032-9699
Andrew P RileyDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-3878-0597

Funding

Institutional Career DevelopmentKL2TR002002 · NCATS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PHILLIPS, SHANE A · 2016 to 2024
$6.8M
Research Training in Natural Product Complementary and Integrative HealthT32AT007533 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Joanna E Burdette, JIMMY ORJALA · 2013 to 2026
$4.3M
NCATS NIH HHS KL2 TR002002NCCIH NIH HHS T32 AT007533
6 · The paper itself

Abstract

The first synthesis of aristoquinoline (

Indexed as

AlkaloidsMolecular StructureNicotinic AntagonistsQuinolinesReceptors, NicotinicStereoisomerismAlkaloidsaristoquinolineNicotinic Antagonistsnicotinic receptor alpha3beta4QuinolinesReceptors, Nicotinic

Identifiers

PMID34292752
PMCPMC9999383

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.