Evidence map›Paper›PMID 34292632›Full record

ArticleJournal of cardiac surgery2021

Extracorporeal membrane oxygenation (ECMO) for critically ill patients with coronavirus disease 2019 (COVID-19): A retrospective cohort study.

Shuanglei Li, Jing Xiong, Zhongtao Du, Wei Lai, Xinhua Ma, Zhichun Feng, Yuan Shi, Xiaoyang Hong, Yundai Chen

Open access · greenAbstract read
In one paragraph

Article in Journal of cardiac surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Shuanglei LiDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China.
Jing XiongDepartment of Neonatology, Affiliated Children's Hospital; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Pediatrics, Chongqing Medical University, Chongqing, China.
Zhongtao DuDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Beijing, China.
Wei LaiSichuan University West China Hospital, Chengdu, Sichuan, China.
Xinhua MaXiangya Hospital, Changsha, Hunan, China.
Zhichun FengDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China.
Yuan ShiDepartment of Neonatology, Affiliated Children's Hospital; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Pediatrics, Chongqing Medical University, Chongqing, China.
Xiaoyang HongDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China.
Yundai ChenDepartment of Cardiology, Chinese PLA General Hospital, Beijing, China.ORCID http://orcid.org/0000-0003-4944-1432
Chinese PLA General Hospital · CNChildren's Hospital of Chongqing Medical University · CNBeijing Anzhen Hospital · CNCentral South University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe role of extracorporeal membrane oxygenatio (ECMO) for rescue therapy of respiratory failure in critically ill coronavirus disease 2019 (COVID-19) patients remains controversial. We aimed to evaluate the clinical outcomes of ECMO in the treatment of COVID-19 compared with conventional ventilation support.

methodsIn this retrospective cohort study, data were collected on extremely critical patients with COVID-19 from January 2020 to March 2020 in intensive care unit of a hospital in charge by national rescue team in Wuhan, China, the epicenter of pandemic. Patients were classified into the ECMO group and the conventional ventilation non-ECMO group. Clinical characteristics, technical characteristics, laboratory results, mortality, and complications of the two groups were analyzed.

results88 patients with extremely critical COVID-19 were screened; 34 received ECMO support and 31 received conventional ventilation support. Both groups had comparable characteristics at baseline in terms of age, gender, and comorbidities. Before ECMO or conventional therapy, patients in the two groups had sever acute respiratory distress syndrome with a mean partial pressure of arterial oxygen to the fraction of inspired oxygen (PaO

conclusionECMO is shown to decrease the mortality of extremely critical ill COVID-19 patients compared with the conventional treatment. Although complications occurred frequently, ECMO could still be a rescue therapy for the treatment of COVID-19 during the pandemic.

Indexed as

COVID-19Extracorporeal Membrane OxygenationCritical IllnessHumansRetrospective StudiesSARS-CoV-2COVID-19ECMOSARS-CoV-2

Identifiers

PMID34292632
PMCPMC8447061
OpenAlexW3183309779

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.