Evidence map›Paper›PMID 34292537›Full record

ArticleRheumatology and therapy2021

Therapeutic Effects of Ba-Duan-Jin versus Pregabalin for Fibromyalgia Treatment: Protocol for a Randomized Controlled Trial.

Yang Yang, Yan-Ting Li, Yu-Ruo Sun, Jing Wang, Yang Li, Jin-Hua Zhang, Juan Jiao, Quan Jiang

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Rheumatology and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03797560 (Comparison the Treatment Effects Between Ba-Duan-Jin and Pregabalin in Patients with Fibromyalgia), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03797560 nacompletednot on this map

Comparison the Treatment Effects Between Ba-Duan-Jin and Pregabalin in Patients with Fibromyalgia

TypeinterventionalSponsorGuang'anmen Hospital of China Academy of Chinese Medical SciencesRan2019 to 2022Enrolled104ConditionsFibromyalgiaArmsBa-Duan-Jin, Pregabalin capsule
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 15 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yang Yang *Psychology Department, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yan-Ting Li *Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yu-Ruo SunDepartment of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Jing WangClinical Evaluation Centre, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yang LiDepartment of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Jin-Hua ZhangPsychology Department, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Juan JiaoDepartment of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. jiao.juan@hotmail.com.
Quan JiangDepartment of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. jiang.quan@hotmail.com.ORCID http://orcid.org/0000-0002-3031-7848
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

the Capital Characteristic Clinical Application Research Project of Beijing Municipal Science and Technology Plan of China Z181100001718153
6 · The paper itself

Abstract

introductionFibromyalgia is characterized by multi-focal pain and is associated with fatigue, unrefreshing sleep and psychological impairment. Pregabalin is one of the most frequently used agents in fibromyalgia treatment. However, it has failed to demonstrate benefit over placebo for reducing fatigue and psychological impairment, and may cause adverse effects (e.g. somnolence, dizziness). "Ba-Duan-Jin" (BDJ) is a common form of "Qigong" exercise for health promotion in China. Growing evidence suggests that BDJ may achieve satisfactory control of fibromyalgia-related symptoms in Chinese patients. Therefore, we wish to ascertain if BDJ could overcome the disadvantages of pregabalin.

methodsA single-blind randomized controlled trial has been designed which will recruit 104 patients with fibromyalgia (age 18-70 years) with a visual analog scale (VAS) pain score of ≥ 40 mm These patients will be randomly assigned to one of two groups: (1) BDJ group (to undertake guided BDJ exercise and take a placebo capsule) or (2) pregabalin group (to take a pregabalin capsule and receive wellness education and guided muscle-relaxation exercises). The primary endpoint will be changes in the VAS score for pain. The secondary endpoints will be changes in the score for the Revised Fibromyalgia Impact Questionnaire, Multidimensional Fatigue Inventory-20, Pittsburgh Sleep Quality Index, Beck II Depression Inventory, Perceived Stress Scale and Short Form-36 Health Survey Questionnaire. These parameters will be assessed at 0, 4, 8, 12 and 24 weeks of follow-up. PLANNED OUTCOMES: Our results are expected to provide more clinical evidence for the beneficial effects of BDJ in treating fibromyalgia.

trial registrationNCT03797560.

Indexed as

Ba-Duan-JinFibromyalgiaFibromyalgia-related symptomsPain managementQigong

Identifiers

PMID34292537
PMCPMC8380613
OpenAlexW3185765704

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.