ArticleForensic science, medicine, and pathology2021
The human intervertebral disc as a source of DNA for molecular identification.
Article in Forensic science, medicine, and pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Human costal cartilage, tooth cavities, and femur nutrient canals-new niches for insects used in forensic entomology.Forensic sciences research · 2025Article
- Decoding Time of Death: Histopathological Dynamics of Intervertebral Discs as a Novel Marker for Postmortem Interval Estimation.Diagnostics (Basel, Switzerland) · 2025Article
- Article
- The intervertebral discs' fibrocartilage as a DNA source for genetic identification in severely charred cadavers.Forensic science, medicine, and pathology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Genetic analyses such as STR-typing are routinely used for identification purposes in forensic casework. Although genotyping techniques only require a minimum amount of DNA to provide a genetic profile, DNA quality differs not only between but also within tissues during ongoing decomposition. Initiated by a recent case where, due to the constitution of the body, preferred tissue was not available or only resulted in a partial and not usable DNA profile, the analysis of intervertebral discs as a source of DNA was considered. As the analysis of this tissue resulted in a high quality DNA profile a further study was performed in which thirty intervertebral discs dissected from bodies in different stages of decay were analyzed. All samples yielded good quality DNA in quantities suitable for STR-based amplification with no or only low degradation indices, resulting in complete genetic profiles. These results demonstrate the robustness of human intervertebral disc tissue as a source of DNA for molecular identification purposes.
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Registered trials
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