ArticleSleep & breathing = Schlaf & Atmung2022
Fatigue is associated with depression independent of excessive daytime sleepiness in the general population.
Article in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 20 citations in OpenAlex.
- Sleep debt and depressive symptoms among workers: the mediating role of fatigue.Frontiers in public health · 2026Article
- The use ofFrontiers in cell and developmental biology · 2026Review
- Differential associations of passively sensed behaviors with in-vivo depression symptoms.Journal of psychopathology and clinical science · 2025Article
- Current situation and related factors of fatigue among doctors and nurses in tertiary general hospitals in Northeast China.Scientific reports · 2025Article
- High fatigue levels among psychiatric outpatients - the validity of the Danish Patient Reported Outcomes Measurement Information System Fatigue Short-Form (PROMISF-SF).Journal of patient-reported outcomes · 2025Article
- The relationship between fatigue, sleep quality, and sleep deprivation.Sleep & breathing = Schlaf & Atmung · 2025Article
- Depressed mood affects the process of biological aging, analyses from the NHANES dataset.Frontiers in aging · 2025Review
- Fatigue or excessive daytime sleepiness: which is more closely related to depression?Sleep & breathing = Schlaf & Atmung · 2024Article
- Evaluating the psychometric properties of the fatigue severity scale using item response theory.BMC psychology · 2023Article
- Subjective sleep quality and fatigue assessment in Polish adult patients with primary immunodeficiencies: A pilot study.Frontiers in immunology · 2022Article
- Distinct Profiles of Morning and Evening Fatigue Co-Occurrence in Patients During Chemotherapy.Nursing researchArticle
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to investigate sleep problems and comorbid conditions associated with fatigue in the general population.
methodsThe data were obtained from a nationwide cross-sectional survey conducted in 2018. The Fatigue Severity Scale was used to assess fatigue. We examined sleep habits, such as workday sleep duration, chronotype, and free-day catch-up sleep, excessive daytime sleepiness (EDS), depression, and other comorbid conditions. We conducted multiple logistic regression analysis with the presence of fatigue as a dependent variable.
resultsOf 2,493 adults aged 19 to 92 years, 50% men, mean age was 47.9 ± 16.4 years. The average workday sleep duration was 7.1 ± 1.1 h, and the prevalence of fatigue was 31%. After adjusting for potential confounders, fatigue was associated with EDS (odds ratio [OR] 3.751, 95% confidence interval [CI] 2.928-4.805), depression (OR 3.736, 95% CI 2.701-5.169), perceived insufficient sleep (OR 1.516, 95% CI 1.249-1.839), free-day catch-up sleep (OR 1.123, 95% CI 1.020-1.235), less alcohol intake (OR 0.570, 95% CI 0.432-0.752), and physical inactivity (OR 0.737, 95% CI 0.573-0.948). On subgroup analysis, fatigue was additionally associated with short workday sleep duration (OR 0.899, 95% CI 0.810-0.997) in individuals without EDS. However, among those with EDS, only depression (OR 2.842, 95% CI 1.511-5.343) and less alcohol intake (OR 0.476, 95% CI 0.247-0.915) were associated with fatigue.
conclusionFatigue was significantly associated with depression independent of EDS. Further research is warranted to better understand the pathophysiological relationship between fatigue, depression, and sleep.
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