Evidence map›Paper›PMID 34292444›Full record

ArticleBulletin of experimental biology and medicine2021

Osteogenic and Regenerative Potential of Free Gingival Graft.

S S Edranov, N Yu Matveeva, S G Kalinichenko

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

S S EdranovDepartment of Histology, Embryology and Cytology, Pacific State Medical University, Ministry of Health of the Russian Federation, Vladivostok, Russia.
N Yu MatveevaDepartment of Histology, Embryology and Cytology, Pacific State Medical University, Ministry of Health of the Russian Federation, Vladivostok, Russia. nymatveeva@mail.ru.
S G KalinichenkoDepartment of Histology, Embryology and Cytology, Pacific State Medical University, Ministry of Health of the Russian Federation, Vladivostok, Russia.
Vladivostok State Medical University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We studied immunolocalization of CD29, CD44, osteocalcin, and TGF-β1 in the bone tissue of the mandible of miniature pigs with extra-bone fixation of a free gingival graft. Three months after surgery, neoosteogenesis foci with high expression of the studied markers were found in the contact area of the free gingival graft with the alveolar bone. The markers were localized in the layer of external circumferential lamellae, on the surface of concentric lamellae of the growing osteons, and in the connective tissue of the Haversian canals. TGF-β1-immunopositive cells predominated in the connective tissue of the Haversian and Volkmann canals and in the adventitia and inner lining of the vascular wall. The established morphochemical patterns of osteogenous cells indicate significant reparative capabilities of a free gingival graft and allows considering it as an effective osteoinductive factor.

Indexed as

Alveolar Bone GraftingAnimalsBiomarkersBone NailsGene ExpressionGingivaHyaluronan ReceptorsIntegrin beta1MaleMandibleOsteocalcinOsteogenesisRegenerationSurgical Fixation DevicesSwineSwine, MiniatureBiomarkersHyaluronan ReceptorsIntegrin beta1OsteocalcinTransforming Growth Factor beta1alveolar ridgebone remodelinggrowth factorshard palateosteoblasts

Identifiers

PMID34292444
OpenAlexW3138366843

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.