Evidence map›Paper›PMID 34292404›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2021

Solid-phase synthesis and evaluation of linear and cyclic ferrocenoyl/ruthenocenoyl water-soluble hexapeptides as potential antibacterial compounds.

Johana Gómez, Diego Sierra, Claudia Ojeda, Sugina Thavalingam, Reece Miller, Fanny Guzmán, Nils Metzler-Nolte

Abstract read
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In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Johana GómezNúcleo de Biotecnología Curauma, Pontificia Universidad Católica de Valparaíso, Av. Universidad 330, Valparaiso, Chile. johana.gomez.u@mail.pucv.cl.
Diego SierraInstituto de Química Y Bioquímica, Facultad de Ciencias, Universidad de Valparaíso, Av. Gran Bretaña 1111, Valparaiso, Chile. diego.sierra@uv.cl.
Claudia OjedaInstituto de Biología, Pontificia Universidad Católica de Valparaíso, Avenida Brasil 2950, Valparaiso, Chile.
Sugina ThavalingamInorganic Chemistry I-Bioinorganic Chemistry, Ruhr University Bochum, Universitӓtsstrasse 150, 44780, Bochum, Germany.
Reece MillerInorganic Chemistry I-Bioinorganic Chemistry, Ruhr University Bochum, Universitӓtsstrasse 150, 44780, Bochum, Germany.
Fanny GuzmánNúcleo de Biotecnología Curauma, Pontificia Universidad Católica de Valparaíso, Av. Universidad 330, Valparaiso, Chile.
Nils Metzler-NolteInorganic Chemistry I-Bioinorganic Chemistry, Ruhr University Bochum, Universitӓtsstrasse 150, 44780, Bochum, Germany.
Pontificia Universidad Católica de Valparaíso · CLRuhr University Bochum · DEUniversity of Valparaíso · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of novel water-soluble short peptide-bioconjugates containing a ferrocenoyl (Fc) or ruthenocenoyl (Rc) unit was synthesized and characterized to combine the unique activity of ferrocene and the isoelectronic ruthenocene with precisely designed peptide structures. We aim at evaluating these bioconjugates as a new class of OrganoMetallic Short AntiMicrobial Peptides (OM-SAMPs). The series of OM-SAMPs was designed with a set of linear and "head-to-tail" cyclic metallocene-based hexapeptides derived from the homo-sequence H-KKKKKK-NH

Indexed as

Solid-Phase Synthesis TechniquesAnti-Bacterial AgentsFerrous CompoundsGram-Negative BacteriaGram-Positive BacteriaMetallocenesMicrobial Sensitivity TestsMolecular StructureOligopeptidesOrganometallic CompoundsSolubilityWaterAnti-Bacterial AgentsferroceneFerrous CompoundsMetallocenesOligopeptidesOrganometallic CompoundsruthenoceneWaterAntimicrobial peptidesFerroceneMinimum inhibitory concentrationOrganometallic peptidesPeptide bioconjugatesRuthenocene

Identifiers

PMID34292404
OpenAlexW3184656439

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.