Evidence map›Paper›PMID 34292135›Full record

ArticleHuman vaccines & immunotherapeutics2022

Effectiveness of an outbreak dose of mumps-containing vaccine in two First Nations communities in Northern Ontario, Canada.

Wallis Rudnick, Sarah Wilson, Jo Ann Majerovich, Michelle Haavaldsrud, Marene Gatali, Cai-Lei Matsumoto, Shelley Deeks

Open access · hybridAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Wallis RudnickCanadian Field Epidemiology Program, Public Health Agency of Canada, Ottawa, Ontario, Canada.ORCID 0000-0003-3457-4216
Sarah WilsonPublic Health Ontario, Toronto, Ontario, Canada.ORCID 0000-0002-8239-0094
Jo Ann MajerovichFirst Nations and Inuit Health - Ontario Region, Indigenous Services Canada, Ottawa, Ontario, Canada.ORCID 0000-0002-4214-0904
Michelle HaavaldsrudFirst Nations and Inuit Health - Ontario Region, Indigenous Services Canada, Ottawa, Ontario, Canada.
Marene GataliFirst Nations and Inuit Health - Ontario Region, Indigenous Services Canada, Ottawa, Ontario, Canada.
Cai-Lei MatsumotoSioux Lookout First Nations Health Authority, Sioux Lookout, Ontario, Canada.
Shelley DeeksPublic Health Ontario, Toronto, Ontario, Canada.ORCID 0000-0002-4055-1398
Indigenous Services CanadaPublic Health Ontario · CAFirst Nations Health and Social Secretariat of Manitoba · CAPublic Health Agency of Canada · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Between 18 Dec 2017 and 27 June 2018, a mumps outbreak occurred in two Canadian Indigenous communities. An outbreak dose of mumps-containing vaccine was offered as part of control measures. We conducted a cohort study and survival analysis to describe the outbreak and evaluate the outbreak dose, extracting vaccination information on all community members (n = 3,135) from vaccination records. There were 70 mumps cases; 56% had received two pre-outbreak vaccine doses. Those who received a pre-outbreak dose more distantly had higher rates of mumps compared to those with more recent doses (adjusted hazard ratio = 3.4 (95%CI: 0.7-20.6) for receipt >20 years before vs. receipt ≤3 years). During the outbreak, 33% (1,010/3,080) of eligible individuals received an outbreak dose. The adjusted hazard ratio for no outbreak dose receipt was 2.7 (95%CI: 1.0-10.1). Our results suggest that an outbreak dose of mumps-containing vaccine may be an effective public health intervention, but further study is warranted.

Indexed as

MeaslesMumpsCohort StudiesDisease OutbreaksHumansMeasles-Mumps-Rubella VaccineOntarioVaccinationMeasles-Mumps-Rubella Vaccineimmunizationmeasles-Mumps-Rubella VaccineMumpsoutbreak dosevaccine Effectiveness

Identifiers

PMID34292135
PMCPMC8920173
OpenAlexW3183356281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.