Evidence map›Paper›PMID 34292058›Full record

ReviewJournal of cutaneous medicine and surgery

A Clinician's Guide to Topical Retinoids.

Melika Motamedi, Ahmad Chehade, Ravina Sanghera, Parbeer Grewal

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of cutaneous medicine and surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Melika Motamedi3158 University of Alberta, Edmonton, AB, Canada.
Ahmad Chehade3158 University of Alberta, Edmonton, AB, Canada.
Ravina Sanghera3158 University of Alberta, Edmonton, AB, Canada.
Parbeer GrewalDivision of Dermatology, University of Alberta, Edmonton, AB, Canada.ORCID https://orcid.org/0000-0001-9296-5851
University of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinoids are defined as molecules that bind to and activate retinoic acid receptors to influence the proliferation and differentiation of cells. Topical retinoids have evolved over the past several decades, being used in multiple dermatological conditions. This review aims to differentiate between synthetic and natural retinoids, discuss the pharmacology behind topical retinoids, highlight clinical applications, and categorize all the commercially available agents, including combination products. Understanding retinoid affinities for unique receptor subtypes can impact clinical decisions, resulting in optimizing treatment and enhancing patient adherence.

Indexed as

Administration, CutaneousAdministration, TopicalDermatologic AgentsHumansOff-Label UseRetinoidsSkin DiseasesDermatologic AgentsRetinoidsacnekeratinizationretinoid

Identifiers

PMID34292058
PMCPMC8750127
OpenAlexW3183646587

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.