Evidence map›Paper›PMID 34291836›Full record

ArticleJournal of veterinary internal medicine2021

Selective symmetrical necrotizing encephalopathy secondary to primary mitochondrial disorder in a cat.

Elena Dell'Era, Margherita Polidori, Marco Bernardini, Stefano Capomaccio, Katia Cappelli, Federica Balducci, Maria T Mandara

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Elena Dell'EraNeurology Unit, AniCura Portoni Rossi Veterinary Hospital, Bologna, Italy.
Margherita PolidoriDepartment of Veterinary Medicine, Neuropathology Laboratory, University of Perugia, Perugia, Italy.
Marco BernardiniNeurology Unit, AniCura Portoni Rossi Veterinary Hospital, Bologna, Italy.ORCID https://orcid.org/0000-0002-8572-0271
Stefano CapomaccioDepartment of Veterinary Medicine, Laboratory of Molecular Biology, University of Perugia, Perugia, Italy.
Katia CappelliDepartment of Veterinary Medicine, Laboratory of Molecular Biology, University of Perugia, Perugia, Italy.
Federica BalducciNeurology Unit, AniCura Portoni Rossi Veterinary Hospital, Bologna, Italy.ORCID https://orcid.org/0000-0002-9561-2477
Maria T MandaraDepartment of Veterinary Medicine, Neuropathology Laboratory, University of Perugia, Perugia, Italy.ORCID https://orcid.org/0000-0003-1501-6163
University of Perugia · ITAzienda USL di Bologna · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 2-year-old female cat was referred for progressive neurological signs indicative of involvement of the prosencephalon, cerebellum, and brainstem. Magnetic resonance imaging identified multifocal, bilateral, symmetrical lesions with strong contrast enhancement, affecting multiple areas of the brain. Neuropathology at necropsy showed demyelination, necrotic lesions, spongiosis, and neuropil edema with reactive astrogliosis and neovascularization. Ultrastructural study indicated mitochondrial polymorphism. Genetic investigations outlined 2 polymorphisms within the tRNA-Leu

Indexed as

Brain DiseasesMitochondrial DiseasesAnimalsBrainDNA, MitochondrialFemaleRNA, Transfer, LeuDNA, MitochondrialRNA, Transfer, Leucatmagnetic resonance imagingmitochondriopathynecrotizing encephalopathytRNA-Leu(UUR) gene

Identifiers

PMID34291836
PMCPMC8478069
OpenAlexW3184771760

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.