Trial reportInternational journal of methods in psychiatric research2021
The effect of a game training intervention on cognitive functioning and depression symptoms in the elderly with mild cognitive impairment: A randomized controlled trial.
Trial report in International journal of methods in psychiatric research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 28 citations in OpenAlex.
- Effectiveness of Nurse-Led Interventions in Older Adults With Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-Analysis.Journal of clinical nursing · 2026Pooled it
- Single non-pharmacological intervention of depression in the elderly with cognitive dysfunction: a systematic review and network meta-analysis.Frontiers in psychiatry · 2025Pooled it
- Association of nonpharmacological interventions for cognitive function in older adults with mild cognitive impairment: a systematic review and network meta-analysis.Aging clinical and experimental research · 2023Pooled it
- Effectiveness of Functional Mobile Games to Enhance Attention in Individuals with Mild Cognitive Impairment: A Study Using The Montreal Cognitive Assessment.Yonsei medical journal · 2025Trial
- Effect of Video Games on Cognitive Performance and Problem-Solving Ability in the Aged with Cognitive Dysfunction: A Randomized Clinical Trial.Iranian journal of medical sciences · 2025Trial
- Trial
- The effect of a game training intervention on cognitive functioning and depression symptoms in the elderly with mild cognitive impairment: A randomized controlled trial.International journal of methods in psychiatric research · 2021Trial
- Article
- Nonlinear Gait Variability and the Role of Cognitive-Physical Exercise in Mitigating Mobility Decline in Institutionalized Older Adults with Cognitive Impairment.Journal of functional morphology and kinesiology · 2026Article
- Effectiveness of a brain exercise program using game-based cognitive enhancement to reduce mild cognitive impairment among older adults in Pathum Thani Province, Thailand: a quasi-experimental study.Osong public health and research perspectives · 2025Article
- Cognitive therapies and their impact on neuropsychiatric symptoms in mild cognitive impairment or dementia: a scoping review.Frontiers in psychology · 2025Review
- Association between wooden toy engagement and cognitive function among Chinese older adults: a cross-sectional study.Frontiers in psychology · 2025Article
- Leisure Activity Interventions on Cognition in Mild Cognitive Impairment Patients: A Meta-Analysis.Neuropsychiatric disease and treatment · 2025Review
- A Tablet-Based Application to Enhance Social Connectedness for Individuals With a Cognitive Impairment: Results From the PRISM-CI Pilot Study.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2024Article
- Effects of Electronic Serious Games on Older Adults With Alzheimer's Disease and Mild Cognitive Impairment: Systematic Review With Meta-Analysis of Randomized Controlled Trials.JMIR serious games · 2024Review
- Effect of Tablet-based Cognitive Intervention on Cognition in Patients With Mild Cognitive Impairment: A Pilot Study.Dementia and neurocognitive disorders · 2023Article
- Cognitive Stimulation as Alternative Treatment to Improve Psychological Disorders in Patients with Mild Cognitive Impairment.Journal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aimed to explore whether game training could improve cognitive functioning and depression symptoms in the elderly affected by mild cognitive impairment (MCI).
methodsA non-blinded randomized controlled trial was conducted. Participants were 72 patients with MCI and depression from a nursing home in Wuhan. Participants were randomized to either the intervention group or the control group (n = 36 each). The intervention group received regular nursing care plus game training for 50 min, three times per week for 8 weeks, whereas the control group received only regular nursing care during the same research period. Cognitive functioning and depression symptoms were tested in both groups at baseline and at the end of the 8-week intervention. We used the Montreal Cognitive Assessment and the 15-item Geriatric Depression Scale to assess cognitive functioning and depression symptoms, respectively.
resultsThe 8-week game training intervention significantly improved the cognitive and depression scores when compared with the control group and baseline scores (p < 0.05). No significant difference was observed in the control group (p > 0.05).
conclusionsOur results suggest that the implementation of game training can improve the cognitive functioning and depression symptoms of the elderly with MCI, indicated that can be widely used.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.