Evidence map›Paper›PMID 34291331›Full record

Trial reportEuropean journal of pediatrics2022

Neurological development and iron supplementation in healthy late-preterm neonates: a randomized double-blind controlled trial.

R Luciano, D M Romeo, G Mancini, S Sivo, C Dolci, C Velli, A Turriziani Colonna, G Vento, C Romagnoli, E M Mercuri

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in European journal of pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Anemia, Iron Supplementation, and the Brain.Clinics in perinatology · 2023
    Review
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

R LucianoNeonatology Unit, Department of Woman and Child Health and Public Health, Child Health Area, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Catholic University of Sacred Heart, Rome, Italy. ritapaolamaria.luciano@policlinicogemelli.it.
D M RomeoPediatric Neurology Unit, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy.
G ManciniDepartment of Woman and Child Health and Public Health, Child Health Area, Catholic University of Sacred Heart, Rome, Italy.
S SivoPediatric Neurology Unit, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy.
C DolciDepartment of Woman and Child Health and Public Health, Child Health Area, Catholic University of Sacred Heart, Rome, Italy.
C VelliPediatric Neurology Unit, Fondazione Policlinico A. Gemelli IRCCS, Rome, Italy.
A Turriziani ColonnaDepartment of Woman and Child Health and Public Health, Child Health Area, Catholic University of Sacred Heart, Rome, Italy.
G VentoNeonatology Unit, Department of Woman and Child Health and Public Health, Child Health Area, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Catholic University of Sacred Heart, Rome, Italy.
C RomagnoliNeonatology Unit, Department of Woman and Child Health and Public Health, Child Health Area, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy.
E M MercuriPediatric Neurology Unit, Department of Woman and Child Health and Public Health, Child Health Area, Fondazione Policlinico Universitario A. Gemelli, IRCCS, Catholic University of Sacred Heart, Rome, Italy.
Agostino Gemelli University Polyclinic · ITUniversità Cattolica del Sacro Cuore · ITIstituti di Ricovero e Cura a Carattere Scientifico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Late-preterm infants (LPT) are at increased risk for long-term neurodevelopmental sequelae and iron deficiency. The aim of the study is to assess the positive effect of iron supplementation on psychomotor development in healthy LPT. We designed a randomized placebo-controlled double-blind trial dividing the newborns into two groups. Every patient was assessed using the Griffiths Mental Development Scales (GMDS)-II edition at 12-month post-conceptional age. The study was performed at the Neonatology Unit of our Hospital, in Italy. Sixty-six healthy LPT infants born between 34

Indexed as

IronIron DeficienciesDietary SupplementsGestational AgeHumansInfantInfant, NewbornInfant, PrematureIronIron deficiencyIron supplementationLate pretermPsychomotor development

Identifiers

PMID34291331
PMCPMC8760203
OpenAlexW3139095151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.