Evidence map›Paper›PMID 34291285›Full record

ReviewBioscience reports2021

Biochemical composition, transmission and diagnosis of SARS-CoV-2.

Rajesh Ahirwar, Sonu Gandhi, Komal Komal, Geeta Dhaniya, Prem Prakash Tripathi, Vyas Madhavrao Shingatgeri, Krishan Kumar, Jai Gopal Sharma, Saroj Kumar

Open access · goldAbstract readReview
In one paragraph

Review in Bioscience reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Rajesh AhirwarDepartment of Environmental Biochemistry, ICMR-National Institute for Research in Environmental Health, Bhopal 462030, India.
Sonu GandhiDiagnostic Laboratory, DBT-National Institute of Animal Biotechnology, Hyderabad 500032, India.
Komal KomalSchool of Biosciences, Apeejay Stya University, Gurugram 122103, India.
Geeta DhaniyaDivision of Endocrinology, CSIR-Central Drug Research Institute, Lucknow 226031, India.
Prem Prakash TripathiCell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, Kolkata 700032, India.
Vyas Madhavrao ShingatgeriSchool of Biosciences, Apeejay Stya University, Gurugram 122103, India.
Krishan KumarDepartment of Chemistry, Motilal Nehru College, University of Delhi, South Campus, New Delhi 110021, India.
Jai Gopal SharmaDepartment of Biotechnology, Delhi Technological University, Delhi 110042, India.
Saroj KumarSchool of Biosciences, Apeejay Stya University, Gurugram 122103, India.ORCID 0000-0002-1886-9674
Apeejay Stya University · INCentral Drug Research Institute · INDelhi Technological University · INICMR National Institute for Research in Environmental HealthIndian Institute of Chemical Biology · INNational Institute of Animal Biotechnology · INUniversity of Delhi · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19) is a life-threatening respiratory infection caused by severe acute respiratory syndrome virus (SARS-CoV-2), a novel human coronavirus. COVID-19 was declared a pandemic by World Health Organization in March 2020 for its continuous and rapid spread worldwide. Rapidly emerging COVID-19 epicenters and mutants of concerns have created mammoth chaos in healthcare sectors across the globe. With over 185 million infections and approximately 4 million deaths globally, COVID-19 continues its unchecked spread despite all mitigation measures. Until effective and affordable antiretroviral drugs are made available and the population at large is vaccinated, timely diagnosis of the infection and adoption of COVID-appropriate behavior remains major tool available to curtail the still escalating COVID-19 pandemic. This review provides an updated overview of various techniques of COVID-19 testing in human samples and also discusses, in brief, the biochemical composition and mode of transmission of the SARS-CoV-2. Technological advancement in various molecular, serological and immunological techniques including mainly the reverse-transcription polymerase chain reaction (RT-PCR), CRISPR, lateral flow assays (LFAs), and immunosensors are reviewed.

Indexed as

COVID-19 TestingCOVID-19COVID-19 Nucleic Acid TestingCOVID-19 Serological TestingHost-Pathogen InteractionsHumansPredictive Value of TestsPrognosisSARS-CoV-2COVID- 19ELISART-PCRSARS-CoV-2Transmission

Identifiers

PMID34291285
PMCPMC8350435
OpenAlexW3185681911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.