Evidence map›Paper›PMID 34291229›Full record

ArticleThe Lancet regional health. Europe2021

Long term outcomes following critical care hospital admission: A prospective cohort study of UK biobank participants

Joanne McPeake, Theodore J Iwashyna, Philip Henderson, Alastair H Leyland, Daniel Mackay, Tara Quasim, Matthew Walters, Michael Harhay, Martin Shaw

Open access · goldAbstract read
In one paragraph

Article in The Lancet regional health. Europe, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Joanne McPeakeIntensive Care Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom.
Theodore J IwashynaCentre for Clinical Management Research, VA Ann Arbor Health System, Ann Arbor, MI, United States of America.
Philip HendersonSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, United Kingdom.
Alastair H LeylandMRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, United Kingdom.
Daniel MackayInstitute of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom.
Tara QuasimIntensive Care Unit, Glasgow Royal Infirmary, Glasgow, United Kingdom.
Matthew WaltersSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, United Kingdom.
Michael HarhayDepartment of Biostatistics, Epidemiology, and Informatics; and Palliative and Advanced Illness Research (PAIR) Center, Perelman School of Medicine, University of Pennsylvania, Pennsylvania, United States.
Martin ShawSchool of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, United Kingdom.
University of Glasgow · GBGlasgow Royal Infirmary · GBInstitute for Medical Informatics and Biostatistics · CHMRC/CSO Social and Public Health Sciences Unit · GBNHS Greater Glasgow and Clyde · GBUniversity of Michigan · US

Funding

Improving the measurement and analysis of long-term, patient-centered outcomes following acute respiratory failureR00HL141678 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HARHAY, MICHAEL OSCAR · 2020 to 2022
$747k
Chief Scientist Office SPHSU13Chief Scientist Office SPHSU17Medical Research Council MC_PC_17228Medical Research Council MC_QA137853Medical Research Council MC_UU_00022/2Medical Research Council MC_UU_12017/13NHLBI NIH HHS R00 HL141678
6 · The paper itself

Abstract

background: This study aimed to understand the impact of a critical care admission on long-term outcomes, compared to other hospitalised patients without a critical care encounter. A secondary aim was to examine the interrelationship between emotional, physical, and social problems during recovery.

methods: We utilised data from the UK Biobank, an on-going, prospective population-based cohort study. We employed propensity score matching to assess differences in outcomes between patients with a critical care encounter and patients admitted to the hospital (first admission to hospital available) without critical care. Structural equation modelling was used to analyse emotional, physical and social outcomes following critical illness and the relationships between these health domains.

findings: Data from 1,618 patients were analysed. The median time to follow-up in the critical care cohort was 4427 days (IQR:788-6146) vs 4516 days (IQR: 811-6369) in the non-critical care, hospitalised cohort. Across the two time periods assessed (pre and post 2000), patients exposed to critical care were more likely to experience mental health issues such as depression (

interpretationThis cohort study has demonstrated that survivors of critical illness have different psycho-social outcomes to matched patients, hospitalised without a critical care encounter.

fundingJM is funded by a THIS.Institute (University of Cambridge) Research Fellowship (PD-2019-02-16). AHL is part of the Social and Public Health Sciences Unit, funded by the Medical Research Council (MC_UU_12017/13) and the Scottish Government Chief Scientist Office (SPHSU13).

Indexed as

Intensive care and emotionalLong-term outcomesRecovery

Identifiers

PMID34291229
PMCPMC8278491
OpenAlexW3169029330

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.